Oliveira Jéssica Pecene, Mencalha Rodrigo, Sousa Carlos Augusto dos Santos, Abidu-Figueiredo Marcelo, Jorge Síria da Fonseca
CEUA, UNIFESO, Teresopolis, RJ, Brazil.
Department of Veterinary Surgery and Anesthesiology, School of Veterinary Medicine, Valenca Higher Education Center, Valenca, RJ, Brazil.
Acta Cir Bras. 2014 Oct;29(10):633-8. doi: 10.1590/s0102-8650201400160002.
To assess pain in the immediate postoperative period in cats submitted into two different celiotomy techniques for ovariohysterectomy.
Fourteen healthy female cats up to three years old with a mean weight 2.75 kg, without breed specification, were used in this double blind experiment. The animals were randomly assigned to two treatments: I- ovariohysterectomy by lateral approach (LA) or II - by midline approach (MA). The anesthesia consisted of acepromazine (0.1 mg.kg-1) and midazolam (0.25mg.kg-1) followed isoflurane vaporization to induce and maintain hypnosis. A bolus of fentanyl (5 μg.kg-1) was administered intravenously to provide intraoperative analgesia. After surgery, pain scores were assessed through a multidimensional composite pain scale at four different times.
Generally all factors related to psychomotor changes and pain expression showed higher scores in cats neutered by LA, but only psychomotor changes and total pain score presented statistical differences (p<0.05). The animals that underwent lateral celiotomy showed higher pain scores, at 1, 4 and 6 hours after surgery.
Multidimensional analgesic scales were highly reliable. There was a tendency for the cats neutered by lateral approach to suffer more postoperative pain, including requiring a large number of analgesic rescues.
评估采用两种不同剖腹术式进行卵巢子宫切除术的猫术后即刻的疼痛情况。
本双盲实验使用了14只年龄不超过3岁、平均体重2.75千克、无品种限定的健康雌性猫。动物被随机分为两组:I - 经侧方入路进行卵巢子宫切除术(LA)或II - 经中线入路(MA)。麻醉由乙酰丙嗪(0.1毫克/千克)和咪达唑仑(0.25毫克/千克)组成,随后进行异氟烷蒸发以诱导和维持麻醉。静脉注射一剂芬太尼(5微克/千克)以提供术中镇痛。术后,在四个不同时间通过多维综合疼痛量表评估疼痛评分。
总体而言,所有与精神运动变化和疼痛表现相关的因素在经LA绝育的猫中得分更高,但只有精神运动变化和总疼痛评分存在统计学差异(p<0.05)。接受侧方剖腹术的动物在术后1、4和6小时疼痛评分更高。
多维镇痛量表高度可靠。经侧方入路绝育的猫有术后疼痛更严重的趋势,包括需要大量的镇痛补救措施。