男男性行为者中肛交时扮演不同角色者感染艾滋病毒的相对风险：基于全球数据的系统评价和荟萃分析

Relative Risk for HIV Infection Among Men Who Have Sex with Men Engaging in Different Roles in Anal Sex: A Systematic Review and Meta-analysis on Global Data.

作者信息

Meng Xiaojun, Zou Huachun, Fan Song, Zheng Benfeng, Zhang Lin, Dai Xin, Deng Minli, Zhang Xuan, Lu Bing

机构信息

Wuxi Center for Disease Control and Prevention, Wuxi, Jiangsu, People's Republic of China.

出版信息

AIDS Behav. 2015 May;19(5):882-9. doi: 10.1007/s10461-014-0921-x.

DOI:10.1007/s10461-014-0921-x

PMID:25319954

Abstract

We systematically reviewed and meta-analyzed global data on the relative risk for HIV infection among men who have sex with men (MSM) engaging in different roles in anal sex. MSM engaging in receptive anal sex only (MRAI) and MSM engaging in both insertive and receptive anal sex (MIRAI) were 6.9 (95 % CI 5.5-8.6) and 4.3 (95 % CI 3.6-5.3) times more likely to have prevalent HIV compared to MSM engaging in insertive anal sex only (MIAI) in 1981-1985. These figures were 1.8 (95 % CI 1.6-2.0) and 2.2 (95 % CI 2.0-2.4) in 1986-2010. Overall, MRAI and MIRAI were 6.2 (95 % CI 3.3-11.8) and 6.6 (95 % CI 3.8-11.7) times more likely to develop incident HIV infection compared to MIAI. MRAI are at higher risk for HIV infection compared to MIAI. HIV prevalence among men engaging in all roles in anal sex is high enough that all MSM should be aware of potential risk.

摘要

我们系统回顾并荟萃分析了全球范围内男男性行为者（MSM）在肛交中扮演不同角色时感染艾滋病毒的相对风险数据。1981 - 1985年期间，仅进行接受性肛交的男男性行为者（MRAI）和既进行插入性又进行接受性肛交的男男性行为者（MIRAI）感染艾滋病毒的流行率分别是仅进行插入性肛交的男男性行为者（MIAI）的6.9倍（95%置信区间5.5 - 8.6）和4.3倍（95%置信区间3.6 - 5.3）。在1986 - 2010年期间，这些数字分别为1.8（95%置信区间1.6 - 2.0）和2.2（95%置信区间2.0 - 2.4）。总体而言，与MIAI相比，MRAI和MIRAI发生艾滋病毒感染的风险分别高6.2倍（95%置信区间3.3 - 11.8）和6.6倍（95%置信区间3.8 - 11.7）。与MIAI相比，MRAI感染艾滋病毒的风险更高。在肛交中扮演各种角色的男性中，艾滋病毒流行率高到所有男男性行为者都应意识到潜在风险。