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中国 U=U 和 PrEP 时代男男性行为者的 HIV 血清学检测结果披露

HIV Serostatus Disclosure Among Men Who Have Sex with Men in China in the Era of U=U and PrEP.

机构信息

Department of Social Medicine and Health Education, School of Public Health, Peking University, Beijing, 100191, China.

School of Public Health, Sun Yat-Sen University, North Campus, 74# Zhongshan 2nd Road, Guangzhou, 510000, China.

出版信息

AIDS Behav. 2022 May;26(5):1477-1488. doi: 10.1007/s10461-021-03502-7. Epub 2021 Oct 25.

Abstract

Given the recent evidence on "Undetectable = Untransmittable" (U=U) and pre-exposure prophylaxis (PrEP), the present study aimed to investigate HIV disclosure behaviors and their associations with sexual risk behaviors and U=U and PrEP awareness among men who have sex with men (MSM) in China. A cross-sectional survey was conducted among 689 MSM recruited through a gay-friendly non-governmental organization located in Chengdu, China in 2018-2019. Information was collected by a structured self-administrated questionnaire. The enrolled sample included 554 (80.4%) participants who were HIV-negative and 135 (19.6%) participants with an unknown HIV status. In terms of disclosure, 41.4% of participants informed all partners about their HIV status all the time (informing behavior), while 30.4% asked all partners about their HIV status all the time (asking behavior). Only one-fifth knew about U=U, but this was not statistically associated with either informing or asking behavior. Half (50.5%) had heard of PrEP but this was not statistically associated with either informing or asking behavior. Common barriers to informing and asking behaviors were lower risk perception of HIV infection, a history of sexually transmitted infections, engagement in receptive sex, and a history of sex with casual partners. We found that both U=U and PrEP awareness and HIV serostatus disclosure were infrequent and not associated in this study of Chinese MSM. These data indicate huge information gaps among MSM in China.

摘要

鉴于最近关于“检测不到即无法传播”(U=U)和暴露前预防(PrEP)的证据,本研究旨在调查中国男男性行为者(MSM)的 HIV 披露行为及其与性行为风险行为以及 U=U 和 PrEP 意识的关系。2018-2019 年,通过位于中国成都的一个同性恋友好型非政府组织,对 689 名 MSM 进行了横断面调查。通过结构化的自我管理问卷收集信息。纳入的样本包括 554 名(80.4%)HIV 阴性参与者和 135 名(19.6%)HIV 状态未知的参与者。在披露方面,41.4%的参与者始终向所有伴侣告知其 HIV 状况(告知行为),而 30.4%的参与者始终询问所有伴侣的 HIV 状况(询问行为)。只有五分之一的人知道 U=U,但这与告知或询问行为没有统计学关联。有一半(50.5%)听说过 PrEP,但这与告知或询问行为没有统计学关联。告知和询问行为的常见障碍是 HIV 感染风险认知较低、性传播感染史、接受性行为以及与偶然伴侣发生性关系的历史。我们发现,在中国 MSM 的这项研究中,U=U 和 PrEP 意识以及 HIV 血清状况披露都不常见,也没有关联。这些数据表明,中国 MSM 存在巨大的信息差距。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27a3/9001537/1ee44c58d21c/10461_2021_3502_Fig1_HTML.jpg

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