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[β-内啡肽和δ-睡眠诱导肽对情绪应激抵抗力的影响]

[Effects of beta endorphin and delta-sleep inducing peptide on resistance to emotional stress].

作者信息

Salieva R M, Koplik E V, Kamenov Z A, Poletaev A B

出版信息

Biull Eksp Biol Med. 1989 Oct;108(10):464-6.

PMID:2532045
Abstract

Enzyme immunoassay was used to study the contents of beta-endorphin and delta-sleep inducing peptide (DSIP) in blood and hypothalamus in rats of Wistar and August lines under acute emotional stress. The stress-resistance of the animals was determined by using preliminary behavior tests. The rats were divided into two groups and predisposed to acute emotional stress. It was found that the contents of these peptides in Wistar-rats, which are more resistant to emotional stress, were higher compared with the August-rats, which are more predisposed to emotional stress. It was shown that the contents of beta-endorphin and DSIP in Wistar-rats is higher than in predisposed Wistar-rats.

摘要

采用酶免疫分析法研究急性情绪应激下Wistar系和奥古斯特系大鼠血液和下丘脑内β-内啡肽及δ-睡眠诱导肽(DSIP)的含量。通过初步行为测试测定动物的应激抗性。将大鼠分为两组并使其处于急性情绪应激状态。结果发现,对情绪应激更具抗性的Wistar系大鼠体内这些肽的含量,高于更易受到情绪应激影响的奥古斯特系大鼠。结果表明,Wistar系大鼠体内β-内啡肽和DSIP的含量高于易受应激影响的Wistar系大鼠。

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