Salieva R M, Koplik E V, Kamenov Z A, Poletaev A B
Biull Eksp Biol Med. 1988 Sep;106(9):264-6.
Enzyme immunoassay was used to study delta-sleep peptide content in blood and hypothalamus in rats of Wistar lines under acute emotional stress. It was found that the content of delta-sleep peptide in blood and hypothalamus of stable rats was higher as compared with rats predisposed to emotional stress. After 1.5-hour emotional stress the content of delta-sleep peptide increased in blood and hypothalamus both in stable rats and predisposed ones. After 3-hour stress there was an increase in delta-sleep peptide content in hypothalamus, and contrary to its decrease in blood in both stable and predisposed animals. It is supposed that delta-sleep peptide along with other oligopeptides is one of the factors determining individual animal resistance to emotional stress, which is supported by significant delta-sleep peptide increase in hypothalamus in stable rats.
采用酶免疫分析法研究急性情绪应激下Wistar系大鼠血液和下丘脑内δ-睡眠肽的含量。结果发现，与易发生情绪应激的大鼠相比，稳定大鼠血液和下丘脑内δ-睡眠肽的含量更高。在1.5小时情绪应激后，稳定大鼠和易应激大鼠血液和下丘脑内δ-睡眠肽的含量均增加。在3小时应激后，下丘脑内δ-睡眠肽含量增加，而在稳定和易应激动物中，其血液中含量均下降。据推测，δ-睡眠肽与其他寡肽一起是决定动物个体对情绪应激抵抗力的因素之一，稳定大鼠下丘脑内δ-睡眠肽显著增加支持了这一点。
