Takeno Shinsuke, Hashimoto Tatsuya, Maki Kenji, Shibata Ryosuke, Shiwaku Hironari, Yamana Ippei, Yamashita Risako, Yamashita Yuichi
Shinsuke Takeno, Tatsuya Hashimoto, Kenji Maki, Ryosuke Shibata, Hironari Shiwaku, Ippei Yamana, Risako Yamashita, Yuichi Yamashita, Department of Gastroenterological Surgery, Fukuoka University Faculty of Medicine, Fukuoka 814-0180, Japan.
World J Gastroenterol. 2014 Oct 14;20(38):13734-40. doi: 10.3748/wjg.v20.i38.13734.
Gastric stump carcinoma was initially reported by Balfore in 1922, and many reports of this disease have since been published. We herein review previous reports of gastric stump carcinoma with respect to epidemiology, carcinogenesis, Helicobacter pylori (H. pylori) infection, Epstein-Barr virus infection, clinicopathologic characteristics and endoscopic treatment. In particular, it is noteworthy that no prognostic differences are observed between gastric stump carcinoma and primary upper third gastric cancer. In addition, endoscopic submucosal dissection has recently been used to treat gastric stump carcinoma in the early stage. In contrast, many issues concerning gastric stump carcinoma remain to be clarified, including molecular biological characteristics and the carcinogenesis of H. pylori infection. We herein review the previous pertinent literature and summarize the characteristics of gastric stump carcinoma reported to date.
胃残端癌最初由巴尔福尔于1922年报道,此后关于这种疾病的许多报告相继发表。我们在此回顾先前关于胃残端癌的报告,内容涉及流行病学、致癌作用、幽门螺杆菌(H. pylori)感染、爱泼斯坦-巴尔病毒感染、临床病理特征及内镜治疗。特别值得注意的是,胃残端癌与原发性胃上部三分之一癌之间未观察到预后差异。此外,内镜下黏膜下剥离术近来已用于早期胃残端癌的治疗。相比之下,关于胃残端癌仍有许多问题有待阐明,包括分子生物学特征及幽门螺杆菌感染的致癌作用。我们在此回顾先前的相关文献,并总结迄今报道的胃残端癌的特征。