Department of General Surgery, The Third People's Hospital of Mianyang Sichuan Mental Health Center, Mianyang, Sichuan, China.
Medicine (Baltimore). 2023 May 19;102(20):e33808. doi: 10.1097/MD.0000000000033808.
Gastric stump carcinoma (GSC) is very exceptional and little known after Whipple procedure, and its diagnosis and treatment are extremely difficult to handle.
The patient, a 68-year-old man, visited our hospital's General surgery outpatient clinic complaining of upper abdominal pain that had been bothering him for half a month. The endoscopy revealed lesions in the stomach residual, and the pathological results suggested adenocarcinoma. The patient underwent Whipple procedure for periampullary adenocarcinoma in the 4th year ago.
The final diagnosis was gastric adenocarcinoma and its pathological stage was Ⅱ A (T3N0M0).
The patient underwent stump gastrectomy and end-to-side esophagojejunostomy (Roux-en-Y reconstruction).
The operation went smoothly and the patient recovered well with only mild bloating and nausea, and the symptoms completely disappeared during the hospital stay.
The development of GSC several years after Whipple procedure is uncommon. This is the first case from China that has received international attention. Early diagnosis is crucial. Surgery is considered to be the most effective treatment for GSC after Whipple procedure if long-term survival is possible and surgical risks are controllable.
胰十二指肠切除术后残胃癌(Gastric stump carcinoma,GSC)非常罕见且鲜为人知,其诊断和治疗极具挑战性。
患者为 68 岁男性,因上腹痛半月余就诊于我院普通外科门诊。胃镜提示残胃病变,病理结果提示腺癌。4 年前因壶腹周围腺癌行胰十二指肠切除术。
最终诊断为胃腺癌,病理分期为ⅡA(T3N0M0)。
行残胃大部切除+残胃空肠端侧吻合术(Roux-en-Y 重建)。
手术顺利,患者恢复良好,仅轻微腹胀、恶心,住院期间症状完全消失。
胰十二指肠切除术后数年发生 GSC 并不常见。这是首例引起国际关注的中国病例。早期诊断至关重要。如果长期生存可能且手术风险可控,手术被认为是胰十二指肠切除术后 GSC 最有效的治疗方法。