慢性丙型肝炎患者肝脏酶和心理健康状况对有氧运动训练的反应
Liver enzymes and psychological well-being response to aerobic exercise training in patients with chronic hepatitis C.
作者信息
Abd El-Kader Shehab M, Al-Jiffri Osama H, Al-Shreef Fadwa M
机构信息
Department of Physical Therapy, Faculty of Applied Medical Sciences, King Abdulaziz University.
Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University.
出版信息
Afr Health Sci. 2014 Jun;14(2):414-9. doi: 10.4314/ahs.v14i2.18.
BACKGROUND
Chronic hepatitis C (CHC) is a medical condition that has broad implications for a person's physical and psychological health.
OBJECTIVE
The aim of this study was to detect changes in liver enzymes and psychological well-being in response to aerobic exercise training in patients with CHC.
MATERIAL AND METHODS
Fifty CHC patients were included in two equal groups. The first group (A) received aerobic exercise training in addition to their regular medical treatment. The second group (B) received no training and only has their regular medical treatment. The program consisted of three sessions per week for three months.
RESULTS
There was a significant decrease in mean values of Alkaline Phosphatase (ALP), Alanine Aminotransferase (ALT), Aspartate Aminotransferase (AST), Gamma - Glutamyltransferase (GGT), Beck Depression Inventory (BDI ) & Profile of Mood States(POMS) and increase in Rosenberg Self-Esteem Scale (RSES) in group (A) after treatments, but the changes in group (B) were not significant. Also, there were significant differences between mean levels of the investigated parameters in group (A) and group (B) at the end of the study.
CONCLUSION
Aerobic exercise training improves hepatic enzymes and psychological well-being in patients with chronic hepatitis C.
背景
慢性丙型肝炎（CHC）是一种对人的身心健康有广泛影响的病症。
目的
本研究旨在检测慢性丙型肝炎患者有氧运动训练后肝酶和心理健康状况的变化。
材料与方法
50名慢性丙型肝炎患者被分为两组，每组人数相等。第一组（A组）在接受常规药物治疗的基础上进行有氧运动训练。第二组（B组）不接受训练，仅接受常规药物治疗。该项目为期三个月，每周进行三次训练。
结果
治疗后，A组碱性磷酸酶（ALP）、丙氨酸氨基转移酶（ALT）、天冬氨酸氨基转移酶（AST）、γ-谷氨酰转移酶（GGT）、贝克抑郁量表（BDI）及情绪状态量表（POMS）的平均值显著下降，罗森伯格自尊量表（RSES）得分升高，而B组的变化不显著。此外，研究结束时，A组和B组各研究参数的平均水平存在显著差异。
结论
有氧运动训练可改善慢性丙型肝炎患者的肝酶水平和心理健康状况。
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