Buster Erik H J C, de Man Robert A
Erasmus MC, afd. Maag-Darm-Leverziekten, Rotterdam.
Ned Tijdschr Geneeskd. 2014;158:A8151.
Routine screening of pregnant women for infection with hepatitis B virus and active-passive immunization of newborns resulted in a dramatic decline in vertical transmission of hepatitis B. A recent study in the Annals of Internal Medicine identified factors associated with failure of active-passive immunization of newborns from hepatitis B virus infected mothers. A further decline in the incidence of vertical transmission of hepatitis B virus may be expected when referral for and initiation of antiviral therapy in the last trimester of pregnancy for selected patients can be optimized.
对孕妇进行常规乙肝病毒感染筛查以及对新生儿进行主动-被动免疫，使得乙肝垂直传播显著下降。《内科学年鉴》最近的一项研究确定了与乙肝病毒感染母亲的新生儿主动-被动免疫失败相关的因素。当针对选定患者在妊娠晚期优化转诊并启动抗病毒治疗时，预计乙肝病毒垂直传播的发生率会进一步下降。
