Kawai K
Nihon Hifuka Gakkai Zasshi. 1989 Aug;99(9):973-84.
Lymphocytes bearing Fc receptors for IgE (Fc epsilon R) and serum IgE were determined on eighty-one patients with atopic dermatitis by immunofluorescence assay using H107 monoclonal antibody and radioimmunosorbent test, respectively. The patients were divided into three groups with mild, moderate, and severe involvement, based on the extent of skin lesions. Both exploratory data analysis and statistical analysis by nonparametric methods showed significant correlations of the percentage of Fc epsilon R+ lymphocytes and serum IgE level with the extent of skin involvement. The nature of skin lesions of the moderate and severe patients also correlated significantly with the percentage of Fc epsilon R+ lymphocytes. There was no correlation between such the nature of skin lesions and serum IgE level.
分别采用H107单克隆抗体免疫荧光法和放射免疫吸附试验，对81例特应性皮炎患者检测了携带IgE Fc受体（FcεR）的淋巴细胞和血清IgE。根据皮肤病变范围，将患者分为轻度、中度和重度受累三组。探索性数据分析和非参数方法的统计分析均显示，FcεR +淋巴细胞百分比和血清IgE水平与皮肤受累程度显著相关。中度和重度患者的皮肤病变性质也与FcεR +淋巴细胞百分比显著相关。皮肤病变性质与血清IgE水平之间无相关性。
