使用光学相干断层扫描产生的正面层成像评估视神经纤维层的解离外观。

Evaluating dissociated optic nerve fiber layer appearance using en face layer imaging produced by optical coherence tomography.

作者信息

Kusuhara Sentaro, Matsumiya Wataru, Imai Hisaori, Honda Shigeru, Tsukahara Yasutomo, Negi Akira

机构信息

Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.

出版信息

Ophthalmologica. 2014;232(3):170-8. doi: 10.1159/000364811. Epub 2014 Oct 15.

DOI:10.1159/000364811

PMID:25323920

Abstract

PURPOSE

To investigate the incidence of and risk factors for a dissociated optic nerve fiber layer (DONFL) appearance after pars plana vitrectomy (PPV).

METHODS

We retrospectively reviewed 189 eyes that underwent PPV with internal limiting membrane removal and judged the presence/absence of an apparent DONFL based on en face layer images produced by spectral-domain optical coherence tomography (SD-OCT).

RESULTS

An apparent DONFL was observed in 47 (24.9%) eyes. The incidence of an apparent DONFL was significantly higher in the macular hole (MH) group (76.5%) than in the non-MH group (epiretinal membrane, diabetic macular edema, retinal vein occlusion, and others; 4.9%; p < 0.001). In the logistic regression analysis, surgical indication for MH was identified as the most significant DONFL risk factor (odds ratio 63.7; p = 1.05 × 10(-8)).

CONCLUSION

Postoperative OCT en face layer imaging clarified that MH eyes are liable to have an apparent DONFL following PPV.

摘要

目的

研究玻璃体切割术（PPV）后视神经纤维层分离（DONFL）外观的发生率及危险因素。

方法

我们回顾性分析了189例行PPV联合内界膜剥除术的患眼，并根据光谱域光学相干断层扫描（SD-OCT）生成的表面层图像判断是否存在明显的DONFL。

结果

47只（24.9%）患眼观察到明显的DONFL。黄斑裂孔（MH）组明显DONFL的发生率（76.5%）显著高于非MH组（视网膜前膜、糖尿病性黄斑水肿、视网膜静脉阻塞等；4.9%；p<0.001）。在逻辑回归分析中，MH的手术指征被确定为最显著的DONFL危险因素（比值比63.7；p=1.05×10⁻⁸）。