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对一名体重1.1千克、孕28周的早产新生儿进行一期杂交姑息治疗,该新生儿患有对位不良型室间隔缺损、左心室流出道梗阻和主动脉缩窄。

Hybrid stage I palliation in a 1.1 kg, 28-week preterm neonate with posterior malalignment ventricular septal defect, left ventricular outflow tract obstruction, and coarctation of the aorta.

作者信息

Karani Kunal B, Zafar Farhan, Morales David L S, Goldstein Bryan H

机构信息

The Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

The Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA

出版信息

World J Pediatr Congenit Heart Surg. 2014 Oct;5(4):603-7. doi: 10.1177/2150135114535272.

Abstract

The hybrid stage I procedure has emerged as a less-invasive alternative to the standard surgical Norwood procedure in the palliation of high-risk hypoplastic left heart syndrome and variants. This approach may also benefit patients requiring complex neonatal repair who have significant anatomic and/or perioperative risk factors that either prevent or complicate durable and robust biventricular circulation from being safely achieved. An extremely low-birth weight (1.1 kg) 28-week gestation preterm neonate with postnatal diagnosis of posterior malalignment ventricular septal defect, severe left ventricular outflow tract obstruction, aortic annular hypoplasia, and aortic arch obstruction underwent initial palliation with a hybrid stage I procedure. In this case, hybrid stage I palliation allowed for both somatic and left heart growth followed by ultimate uncomplicated biventricular repair.

摘要

对于高危型左心发育不全综合征及其变异型的姑息治疗,杂交一期手术已成为标准外科诺伍德手术的一种侵入性较小的替代方法。这种方法可能也有利于那些需要复杂新生儿修复的患者,这些患者具有显著的解剖和/或围手术期风险因素,这些因素要么会妨碍安全实现持久且强健的双心室循环,要么会使其变得复杂。一名孕28周、极低出生体重(1.1千克)的早产儿,出生后诊断为对位不良型室间隔缺损、严重左心室流出道梗阻、主动脉瓣环发育不全和主动脉弓梗阻,接受了杂交一期手术进行初始姑息治疗。在这个病例中,杂交一期姑息治疗使体循环和左心得以生长,随后最终顺利进行了双心室修复。

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