Institute for Sport and Physical Activity Research, Dept of Sport Science and Physical Activity, University of Bedfordshire, Bedford, United Kingdom.
J Phys Act Health. 2015 Aug;12(8):1148-52. doi: 10.1123/jpah.2014-0311. Epub 2014 Oct 13.
It is unclear whether cardiorespiratory fitness (CRF) is independently linked to cardiometabolic risk in children. This study investigated a) the association between CRF level and presence of cardiometabolic risk disorders using health-related cut points, and b) whether these associations were mediated by abdominal adiposity in children.
This was a cross-sectional design study. Anthropometry, biochemical parameters and CRF were assessed in 147 schoolchildren (75 girls) aged 10 to 14 years. CRF was determined using a maximal cycle ergometer test. Children were classified as 'fit' or 'unfit' according to published thresholds. Logistic regression was used to investigate the odds of having individual and clustered cardiometabolic risk factors according to CRF level and whether abdominal adiposity mediated these associations.
Children classified as unfit had increased odds of presenting individual and clustered cardiometabolic risk factors (P < .05), but these associations no longer remained after adjusting for abdominal adiposity (P > .05).
This study suggests that the association between CRF and cardiometabolic risk is mediated by abdominal adiposity in 10- to 14-year-old children and that abdominal adiposity may be a more important determinant of adverse cardiometabolic health in this age group.
心肺适能（CRF）与儿童代谢心血管风险之间的关系尚不清楚。本研究旨在：a）使用健康相关切点，探讨 CRF 水平与代谢心血管风险障碍之间的关联；b）评估这些关联是否通过儿童腹部肥胖来介导。
这是一项横断面设计研究。对 147 名 10-14 岁的学龄儿童（75 名女孩）进行了人体测量、生化参数和 CRF 评估。CRF 采用最大循环测功仪测试确定。根据已发表的标准，将儿童分为“健康”或“不健康”。使用逻辑回归分析了根据 CRF 水平和腹部肥胖情况，存在单个和聚集性代谢心血管危险因素的几率，以及这些关联是否通过腹部肥胖来介导。
被归类为不健康的儿童发生单个和聚集性代谢心血管危险因素的几率增加（P<.05），但调整腹部肥胖后，这些关联不再存在（P>.05）。
本研究表明，10-14 岁儿童的 CRF 与代谢心血管风险之间的关联可通过腹部肥胖来介导，并且腹部肥胖可能是该年龄段不良代谢心血管健康的更重要决定因素。
