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化脓性肉芽肿——青春期前阴道出血的一种罕见表现。病例报告及文献复习

Pyogenic granuloma, an unusual presentation of peripubertal vaginal bleeding. Case report and review of the literature.

作者信息

Barasoain-Millán Alberto, Rodriguez-Contreras Francisco Javier, Guerrero-Fernandez Julio, Merino Maria Beato, Gonzalez-Casado Isabel

出版信息

J Pediatr Endocrinol Metab. 2015 Mar;28(3-4):443-7. doi: 10.1515/jpem-2014-0029.

DOI:10.1515/jpem-2014-0029
PMID:25324441
Abstract

Pyogenic granuloma, also named lobular capillary hemangioma, is a common proliferative vascular lesion known as a benign condition despite its rapid growth. It may appear in any cutaneous or mucosal surface but is usually restricted to the oral cavity. It is characterized by a friable mulberry-like lesion that can be sessile or pedunculated. Bleeding is usually its first clinical manifestation. Locations on respiratory, digestive and genital tracts are uncommon and sporadic. We describe the occurrence of an intravaginal pyogenic granuloma in a peripubertal girl with recurrent vaginal bleeding. This is the first reported case of a genital tract lobular capillary hemangioma in pediatric age to our knowledge. Therefore, we suggest this entity in the differential diagnosis of an unclear peripubertal vaginal bleeding.

摘要

化脓性肉芽肿,也称为小叶性毛细血管瘤,是一种常见的增生性血管病变,尽管生长迅速,但属于良性疾病。它可出现在任何皮肤或黏膜表面,但通常局限于口腔。其特征为质地脆的桑葚样病变,可为无蒂或有蒂。出血通常是其首发临床表现。呼吸道、消化道和生殖道的发病部位不常见且呈散发性。我们描述了一例青春期前女孩阴道内出现化脓性肉芽肿并伴有反复阴道出血的病例。据我们所知,这是儿科年龄组首例报道的生殖道小叶性毛细血管瘤病例。因此,我们建议在青春期前不明原因阴道出血的鉴别诊断中考虑这一疾病。

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