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儿童口腔化脓性肉芽肿的不典型临床表现、镜下表现和免疫组化。

Unusual clinical presentation, microscopy and immunohistochemistry of oral pyogenic granuloma in a paediatric patient.

机构信息

Pediatric and Preventive Dentistry, CDER, AIIMS, New Delhi, Delhi, India.

Pediatric and Preventive Dentistry, CDER, AIIMS, New Delhi, Delhi, India

出版信息

BMJ Case Rep. 2024 Aug 21;17(8):e260483. doi: 10.1136/bcr-2024-260483.

DOI:10.1136/bcr-2024-260483
PMID:39174046
Abstract

An unusual clinical presentation of any pathology prompts a diagnostic dilemma, which further brings challenges in treatment planning. Pyogenic granuloma (microscopically lobular capillary haemangioma) is a benign vascular tumour that commonly involves the skin and mucous membranes and usually manifests as a solitary papule with a friable pedunculated base. Rapid exophytic growth and an ulcerated surface with bleeding on provocation are characteristic, with a gingival predominance for the site. This case report aims to elaborate on an unusual clinical presentation of oral pyogenic granuloma in a middle-childhood female patient. The clinical and radiographic characteristics of the lesion were unremarkable to the diagnosis but rather mimicked other intraoral lesions. It is histopathology that could solve the puzzle with the microscopic and immunohistochemical findings that rendered the final diagnosis of lobular capillary haemangioma.

摘要

任何病理学的不寻常临床表现都会引发诊断难题,这进一步给治疗计划带来挑战。化脓性肉芽肿(显微镜下小叶状毛细血管血管瘤)是一种良性血管肿瘤,通常累及皮肤和粘膜,通常表现为单个丘疹,带有易碎的有蒂基底。快速外生性生长和溃疡表面,刺激后出血是其特征,龈部是其好发部位。本病例报告旨在阐述一名中年女性患者口腔化脓性肉芽肿的不寻常临床表现。病变的临床和影像学特征对诊断无明显意义,但更类似于其他口腔内病变。正是组织病理学通过显微镜和免疫组织化学检查结果解决了这个难题,最终诊断为小叶状毛细血管血管瘤。

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BMJ Case Rep. 2024 Aug 21;17(8):e260483. doi: 10.1136/bcr-2024-260483.
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