Pediatric Neurology Unit, Department of Neurosciences, Tor Vergata University , Rome , Italy.
Institut National de la Santé et de la Recherche Médicale, Mediterranean Institute of Neurobiology (INMED) , Marseille , France.
Front Cell Neurosci. 2014 Sep 29;8:309. doi: 10.3389/fncel.2014.00309. eCollection 2014.
New progresses into the molecular and cellular mechanisms of autism spectrum disorders (ASDs) have been discussed in 1 day international symposium held in Pavia (Italy) on July 4th, 2014 entitled "synapses as therapeutic targets for autism spectrum disorders" (satellite of the FENS Forum for Neuroscience, Milan, 2014). In particular, world experts in the field have highlighted how animal models of ASDs have greatly advanced our understanding of the molecular pathways involved in synaptic dysfunction leading sometimes to "synaptic clinical trials" in children.
2014 年 7 月 4 日,在意大利帕维亚举行的题为“突触作为自闭症谱系障碍的治疗靶点”(FENS 神经科学论坛卫星会议,米兰,2014 年)的 1 天国际研讨会上,讨论了自闭症谱系障碍(ASD)的分子和细胞机制的新进展。特别是,该领域的世界专家强调了 ASD 动物模型如何极大地促进了我们对涉及突触功能障碍的分子途径的理解,有时导致儿童的“突触临床试验”。