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阿塞那平诱发的不宁腿综合征:与静坐不能的鉴别。

Asenapine-induced restless legs syndrome: differentiation from akathisia.

作者信息

McCall W Vaughn, Riley Mary Anne, Hodges Chelsea, McCloud Laryssa, Phillips Marjorie, Rosenquist Peter B

机构信息

Department of Psychiatry and Health Behavior, The Medical College of Georgia, Georgia Regents University, Augusta, GA.

Pharmacy Department, Georgia Regents Medical Center, Augusta, GA.

出版信息

J Clin Sleep Med. 2014 Dec 15;10(12):1341-2. doi: 10.5664/jcsm.4296.

Abstract

Akathisia and restless legs syndrome (RLS) share some common clinical features and a common relationship with dopamine dysfunction. However, the underlying causes and appropriate treatments for akathisia and RLS are different. Herein we describe a case of RLS that was precipitated by a single dose of asenapine, which is an atypical antipsychotic, and dissect the features that support the contention that this was indeed a case of RLS and not akathisia.

摘要

静坐不能与不宁腿综合征(RLS)有一些共同的临床特征,且与多巴胺功能障碍存在共同关联。然而,静坐不能和RLS的潜在病因及恰当治疗方法有所不同。在此我们描述一例由单剂量阿立哌唑(一种非典型抗精神病药物)诱发的RLS病例,并剖析支持该病例确实为RLS而非静坐不能这一观点的特征。

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本文引用的文献

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Asenapine: a clinical review of a second-generation antipsychotic.阿塞那平:一种第二代抗精神病药物的临床评价。
Clin Ther. 2012 May;34(5):1023-40. doi: 10.1016/j.clinthera.2012.03.002. Epub 2012 Apr 10.
5
Akathisia and second-generation antipsychotic drugs.静坐不能与第二代抗精神病药物
Curr Opin Psychiatry. 2009 May;22(3):293-99. doi: 10.1097/yco.0b013e32832a16da.

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