Monroy Jose Efren Gonzalez, Orbach Darren B, VanderVeen Deborah
Children's Hospital , Boston, Massachusetts , USA.
Semin Ophthalmol. 2014 Sep-Nov;29(5-6):429-33. doi: 10.3109/08820538.2014.959188.
The purpose of this paper is to perform a systematic review of the published literature on complications of intra-arterial chemothrapy (IAC) for the treatment of retinoblastoma.
A literature search was performed using the Pubmed database using the terms. Complications were divided into extraocular and intraocular.
A total of 117 articles were found using this Pubmed search method; 35 articles were selected for review as they describe specifical complications of IAC for retinoblastoma. A variety of extraocular and intraocular complications were reported and discussed.
IAC for the treatment of retinoblastoma is a technique that has been gaining popularity in recent years, but is not without complications. Continued research is warranted to further improve current techniques and delivery of chemotherapeutic agents into the eye.
本文旨在对已发表的关于动脉内化疗（IAC）治疗视网膜母细胞瘤并发症的文献进行系统综述。
使用Pubmed数据库，通过相关检索词进行文献检索。并发症分为眼外并发症和眼内并发症。
使用这种Pubmed检索方法共找到117篇文章；35篇文章被选入综述，因为它们描述了IAC治疗视网膜母细胞瘤的特定并发症。报告并讨论了各种眼外和眼内并发症。
IAC治疗视网膜母细胞瘤是近年来越来越受欢迎的一种技术，但并非没有并发症。有必要继续开展研究，以进一步改进当前技术，并将化疗药物输送到眼内。
