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[结核病化疗的现代状况]

[Modern status of chemotherapy of tuberculosis].

作者信息

Krieger H G

出版信息

Offentl Gesundheitswes. 1989 Nov;51(11):698-704.

PMID:2532723
Abstract

The state of the art in the drug treatment of tuberculosis has changed into a speciality. The decision for using the traditional or the modern regimens of chemotherapy require a differential indication, to be performed by a specialist only. The applicability of update short-course regimens of chemotherapy is permissible under special conditions only. The treatment constantly requires the combination of 3, 4 or 5 antituberculosis drugs, including INH and RMP as far as practicable. The duration of treatment is determined by the applied combination of drugs. The effectiveness of the therapy is high. It must be tested periodically by bacteriological examinations. The new therapeutic short-course regimens of chemotherapy involved a substantial shortening of the duration of disease, of hospitalisation and of work disablement, and with it a considerable cost reduction.

摘要

结核病药物治疗的技术水平已发展成为一门专业学科。决定采用传统化疗方案还是现代化疗方案需要进行鉴别诊断,且只能由专科医生来进行。仅在特殊情况下才允许采用更新的短程化疗方案。治疗始终需要联合使用3、4或5种抗结核药物,尽可能包括异烟肼和利福平。治疗持续时间由所应用的药物组合决定。该疗法的有效性很高。必须定期通过细菌学检查来检测疗效。新的短程化疗方案大大缩短了疾病持续时间、住院时间和工作残疾时间,同时大幅降低了成本。

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