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[结核病的治疗]

[Therapy of tuberculosis].

作者信息

Eier A, Grass S

机构信息

Internen Abteilung, Pulmologischen Zentrums der Stadt Wien.

出版信息

Wien Med Wochenschr. 1994;144(8-9):186-8.

PMID:7941607
Abstract

The treatment of tuberculosis consists of a combination of at least 3 antituberculosis drugs to prevent occurrence of resistance. Each drug is discussed in detail. Different therapy regimens are described taking into consideration ethnic origin, compliance and underlying diseases of the patients. Standard therapy consists of a short course therapy including rifampicin, isoniazid and pyrazinamide for 6 months. Duration of therapy is extended in immunocompromised patients and in particular organ manifestations of the disease (i.e. meningitis etc.). Intermittent therapy improves compliance of the patients. Four-drug-regimens are recommended until the results of drug susceptibility tests are available in patients originating of countries with high prevalence of resistant strains.

摘要

结核病的治疗包括至少三种抗结核药物联合使用,以防止耐药性的产生。每种药物将详细讨论。会根据患者的种族、依从性和基础疾病描述不同的治疗方案。标准治疗包括一个短期疗程,即使用利福平、异烟肼和吡嗪酰胺治疗6个月。免疫功能低下的患者以及疾病的特定器官表现(如脑膜炎等)的治疗疗程会延长。间歇疗法可提高患者的依从性。对于来自耐药菌株高流行国家的患者,在药敏试验结果出来之前,推荐使用四联疗法。

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