Shrestha Anne, Newton Katie, Benbow Emyr, Kushwaha Rajeev
Department of Surgery, Manchester Royal Infirmary, Oxford Road, Manchester, M13 9WL.
JNMA J Nepal Med Assoc. 2013 Oct-Dec;52(192):627-30.
Kikuchi-Fujimoto disease, or histiocytic necrotising lymphadenopathy of unknown aetiology, is a rare, benign and self-limiting cause of lymphadenopathy often involving the cervical nodes, and rarely presenting with mesenteric lymphadenopathy. We present a 26-year-old Caucasian male, who presented with right iliac fossa pain and low grade pyrexia, mimicking acute appendicitis. He underwent a laparatomy and an extended right hemi-colectomy for a caecal mass. Histology of the specimen showed lymph nodes with extensive areas of necrosis, with abnormal architecture suggesting Kikuchi-Fujimoto lymphadenopathy. This was further confirmed by immunohistochemistry. In this context maintenance of a high index of suspicion of this condition can avoid major surgical interventions. We describe the management of our case of Kikuchi-Fujimoto's disease involving the mesenteric nodes and provide an up to date review of the pertinent literature on this subject.
菊池-藤本病，即病因不明的组织细胞坏死性淋巴结病，是一种罕见的、良性的、自限性的淋巴结病病因，常累及颈部淋巴结，很少表现为肠系膜淋巴结病。我们报告一名26岁的白种男性，他表现为右下腹疼痛和低热，酷似急性阑尾炎。他因盲肠肿物接受了剖腹手术和扩大右半结肠切除术。标本组织学检查显示淋巴结有广泛坏死区域，结构异常提示菊池-藤本病淋巴结病。免疫组化进一步证实了这一点。在这种情况下，对该病保持高度怀疑指数可避免重大手术干预。我们描述了我们这例累及肠系膜淋巴结的菊池-藤本病的治疗，并对该主题的相关文献进行了最新综述。
