新生儿甲状腺大小的超声评估。
Sonographic evaluation of the thyroid size in neonates.
作者信息
Freire Ronald, Monte Osmar, Tomimori Eduardo Kiyoshi, Catarino Regina Maria, Sterza Thais, Rocha Thatyana, Pereira Katia Cristine Carvalho, Mattos Hortensio Simões, Fagundes Leonardo Barros, Liberato Marcelo Martins, Dos Santos Luiz Wagner Rodrigues, Pereira Adeberto, Cintra Terezinha, Hegner Christina, Lube Daniela, Murad Mylene
机构信息
Santa Casa de São Paulo Medical School, São Paulo; Brazil and Radiology Service, Cassiano Antonio Moraes Teaching Hospital of the Federal University of Espirito Santo (HUCAM-UFES), Vitória-ES, Brazil.
Endocrinology and Metabolism Discipline in Santa Casa de São Paulo Medical School, São Paulo-Brazil, Brazil.
出版信息
J Clin Ultrasound. 2015 May;43(4):224-229. doi: 10.1002/jcu.22244. Epub 2014 Oct 18.
PURPOSE
To validate the use of the ratio between the total transverse diameters of the thyroid lobes (Th) and the width of the trachea (Tr)-the Th:Tr or Yasumoto ratio-as a sonographic method for estimating thyroid size, and to determine reference values for this ratio and for thyroid volume in neonates.
METHODS
In this cross-sectional study, we evaluated thyroid size according to the Yasumoto ratio and the thyroid volume calculated with the ellipsoid formula in 125 healthy, euthyroid, iodine-sufficient, full-term neonates.
RESULTS
The mean thyroid gland volume was 1.00 ml (95% confidence interval, 0.95-1.03 ml), and the mean Yasumoto ratio was 2.29 (95% confidence interval, 2.21-2.31). The lower- and upper-limit results falling within 2 SDs of the mean were 0.45 ml and 1.53 ml for the volume and 1.71 and 2.87 for the ratio.
CONCLUSIONS
In full-term, euthyroid, iodine-sufficient neonates, the normal reference interval for thyroid volume measured on sonography was 0.45-1.53 ml and that for the Yasumoto ratio was 1.71-2.87. A ratio of 1.7 may be applied as the cutoff value for sonographic diagnosis of thyroid dysgenesis in full-term neonates with congenital hypothyroidism. © 2014 Wiley Periodicals, Inc. J Clin Ultrasound 43:224-229, 2015.
目的
验证使用甲状腺叶总横径（Th）与气管宽度（Tr）之比——即Th:Tr或安本比值，作为一种超声方法来评估甲状腺大小，并确定该比值及新生儿甲状腺体积的参考值。
方法
在这项横断面研究中，我们根据安本比值评估了125例健康、甲状腺功能正常、碘充足的足月新生儿的甲状腺大小，并使用椭球体公式计算了甲状腺体积。
结果
甲状腺平均体积为1.00 ml（95%置信区间为0.95 - 1.03 ml），安本比值的平均值为2.29（95%置信区间为2.21 - 2.31）。体积的下限和上限结果在平均值的2个标准差范围内，分别为0.45 ml和1.53 ml，比值的下限和上限分别为1.71和2.
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