Moghadam Saede Atarbashi, Khodayari Abbas, Mokhtari Sepideh
Department of Oral and Maxillofacial Pathology, Dental School of Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Oral and Maxillofacial Surgery, Dental School of Shahid Beheshti University of Medical Sciences, Tehran, Iran.
J Oral Maxillofac Pathol. 2014 May;18(2):308-11. doi: 10.4103/0973-029X.140915.
Leiomyosarcoma (LMS) is a malignant soft tissue tumor that exhibits smoothmuscle differentiation. Its occurrence in the oral cavity is exceedingly rare. This article presents a 67-year-old woman with 9-month history of a painful tumoral lesion on the right side of mandible. Tumor was composed of fascicles of spindle-shaped cells with cigar-shaped nuclei and eosinophilic cytoplasm. Immunohistochemistry showed that tumor cells were positive for smooth muscle actin (SMA) and desmin. The findings were consistent with the diagnosis of LMS.
平滑肌肉瘤(LMS)是一种表现出平滑肌分化的恶性软组织肿瘤。它在口腔中的发生极为罕见。本文介绍了一名67岁女性,其右侧下颌骨有一个疼痛性肿瘤病变,病史9个月。肿瘤由梭形细胞束组成,细胞核呈雪茄状,细胞质嗜酸性。免疫组织化学显示肿瘤细胞平滑肌肌动蛋白(SMA)和结蛋白呈阳性。这些发现与LMS的诊断一致。