鼻外鼻孢子虫病的细胞诊断：来自流行地区的16例病例研究

Cytodiagnosis of Extra-nasal Rhinosporidiosis: A Study of 16 Cases from Endemic Area.

作者信息

Pal Subrata, Chakrabarti Srabani, Biswas Biplab Kr, Sinha Rajani, Rakshit Arindam, Das Purna Chandra

机构信息

Department of Pathology, Bankura Sammilani Medical College, Bankura, India.

Department of Pathology, Bardwan Medical College, Burdwan, West Bengal, India.

出版信息

J Lab Physicians. 2014 Jul;6(2):80-3. doi: 10.4103/0974-2727.141501.

DOI:10.4103/0974-2727.141501

PMID:25328331

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4196368/

Abstract

CONTEXT

Extra-nasal rhinosporidiosis is not uncommon in endemic region like India. Clinical presentations of extra-nasal rhinosporidiosis lesion often lead to diagnostic dilemma. Cytology can help in the preoperative diagnosis of such lesions.

AIMS

The aims of our study were to find the clinico-pathological presentation of extra-nasal rhinosporidiosis and to evaluate the role of cytology in diagnosing these lesions preoperatively.

SETTINGS AND DESIGN

Fine-needle aspiration cytology is often used for preoperative diagnosis of sub-cutaneous lesions of the head and neck region. This retrospective study was designed to include the cytologically diagnosed cases of rhinosporidiosis and to compare with final histopathology of the lesions.

MATERIALS AND METHODS

A total of 21 cases of extra-nasal rhinosporidiosis were diagnosed in our study period of 18 months. Cytology was approached in 17 cases and 16 cases were diagnosed as rhinosporidiosis, which were included in the study group. Twelve cases were sampled by fine-needle aspiration and four cases by scrap technique. Histopathological confirmation was possible in all cytologically diagnosed cases.

RESULTS

Head and neck region were involved in 15 cases and only one case was on the skin of right upper arm. Orbital region was the most common extra-nasal site of involvement. Most of the cases (13 cases, 81.25%) belonged to the age group of 11-30 years. All cytologicaly diagnosed cases of rhinosporidiosis were concordant with histopathology. Only one false-negative case was cytologically diagnosed as suppurative inflammatory lesion. Sensitivity and specificity of cytology in diagnosis of extra-nasal rhinosporidiosis were 94.11% and 100% respectively.

CONCLUSIONS

Extra-nasal rhinosporidiosis is an important differential diagnosis of nodular, polypoid mass of head-neck-face region. Cytology can be used as an important tool in preoperative diagnosis of extra-nasal rhinosporidiosis.

摘要

背景

鼻外鼻孢子虫病在印度等流行地区并不罕见。鼻外鼻孢子虫病病变的临床表现常常导致诊断困境。细胞学检查有助于此类病变的术前诊断。

目的

我们研究的目的是找出鼻外鼻孢子虫病的临床病理表现，并评估细胞学在术前诊断这些病变中的作用。

设置与设计

细针穿刺细胞学检查常用于头颈部皮下病变的术前诊断。本回顾性研究旨在纳入经细胞学诊断的鼻孢子虫病病例，并与病变的最终组织病理学结果进行比较。

材料与方法

在我们为期18个月的研究期间，共诊断出21例鼻外鼻孢子虫病病例。17例进行了细胞学检查，其中16例被诊断为鼻孢子虫病，纳入研究组。12例通过细针穿刺取样，4例通过刮片技术取样。所有经细胞学诊断的病例均获得了组织病理学证实。

结果

15例病变累及头颈部，仅1例位于右上臂皮肤。眼眶区域是最常见的鼻外受累部位。大多数病例（13例，81.25%）年龄在11至30岁之间。所有经细胞学诊断的鼻孢子虫病病例与组织病理学结果一致。只有1例假阴性病例在细胞学检查中被诊断为化脓性炎性病变。鼻外鼻孢子虫病诊断中细胞学检查的敏感性和特异性分别为94.11%和100%。