Senaratne Tissa, Edussuriya Kapila, Dhanapala Mangala, Bandara Ashoka, Arseculeratne Sarath
Eye Centre, General Hospital, Kandy, Sri Lanka.
Department of Microbiology, Faculty of Medicine, University of Peradeniya, Sri Lanka.
Eye Brain. 2011 Jan 12;3:1-4. doi: 10.2147/EB.S13342. eCollection 2011.
A case of ocular (bulbar) rhinosporidiosis is described; its unusual features included a) the rapid development of a primary, rhinosporidial lesion with a scleral staphyloma, close to but noncontiguous with the rhinosporidial lesion, 3 weeks after exposure to a lacustrine reservoir, the putative source of the pathogen ; b) ocular coherence tomography which revealed no retinal abnormalities unlike in previous cases reported from Sri Lanka; c) atypical histopathology that resulted in an initial mis-diagnosis of chronic inflammation with mucus cysts and a missed diagnosis of rhinosporidiosis; the rhinosporidial etiology was confirmed on replicate histopathological sections of the ocular mass. The pitfalls of histopathological diagnosis of rhinosporidiosis are pointed out.
本文描述了一例眼部(眼球)鼻孢子虫病病例;其不寻常的特征包括:a)在接触湖泊蓄水池(推测为病原体来源)3周后,原发性鼻孢子虫病变迅速发展,并伴有巩膜葡萄肿,该巩膜葡萄肿靠近鼻孢子虫病变但与之不连续;b)眼部相干断层扫描显示视网膜无异常,这与斯里兰卡先前报道的病例不同;c)非典型组织病理学表现导致最初误诊为伴有黏液囊肿的慢性炎症,漏诊了鼻孢子虫病;眼部肿物的重复组织病理学切片证实了鼻孢子虫病因。文中指出了鼻孢子虫病组织病理学诊断的陷阱。