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一名患有镰状细胞病且近期接受全髋关节置换术的青少年双侧肺栓塞:病例报告及文献复习

Bilateral pulmonary embolism in an adolescent with sickle cell disease and a recent total hip arthroplasty: a case report and review of the literature.

作者信息

Burnham Jeremy M, Broussard Marlene, Milbrandt Todd

机构信息

University of Kentucky Department of Orthopaedic Surgery and Sports Medicine.

Louisiana State University Health Sciences Center - Shreveport Department of Pediatrics.

出版信息

Iowa Orthop J. 2014;34:107-10.

PMID:25328468
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4127743/
Abstract

Pulmonary embolism is a life-threatening but treatable condition. Factors such as hypercoagulability and recent lower extremity surgery are associated with a higher incidence of thrombus formation and pulmonary embolism. Patients with sickle cell disease have a baseline hypercoaguable state and are at a greater risk forming deep vein thrombosis and pulmonary embolism than the general population. This increased risk is rarely cited in the literature. We describe a sickle cell patient two-weeks status-post total hip arthroplasty who presented with bilateral pulmonary embolism complaining of chest and shoulder pain. We highlight the need to include pulmonary embolism in the differential diagnosis of all sickle cell patients complaining of chest pain.

摘要

肺栓塞是一种危及生命但可治疗的疾病。高凝状态和近期下肢手术等因素与血栓形成和肺栓塞的发生率较高有关。镰状细胞病患者存在基线高凝状态,与普通人群相比,发生深静脉血栓形成和肺栓塞的风险更高。这种增加的风险在文献中很少被提及。我们描述了一名全髋关节置换术后两周的镰状细胞病患者,该患者出现双侧肺栓塞,主诉胸痛和肩痛。我们强调,对于所有主诉胸痛的镰状细胞病患者,在鉴别诊断中都需要考虑肺栓塞。

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本文引用的文献

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Beyond the definitions of the phenotypic complications of sickle cell disease: an update on management.超越镰状细胞病表型并发症的定义:管理更新
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Trends in case fatality rate in pulmonary embolism according to stability and treatment.根据稳定性和治疗方法的不同,肺栓塞病死率的趋势。
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