Atkinson Andrew L, Pursell Nicole, Sisay Abinet
Department of Obstetrics and Gynecology, Jersey Shore University Medical Center, 1945 Route 33, Neptune, NJ 07753, USA.
Department of Obstetrics and Gynecology, Debre Markos Referral Hospital, Debre Markos, Ethiopia.
Case Rep Obstet Gynecol. 2014;2014:793534. doi: 10.1155/2014/793534. Epub 2014 Sep 25.
Since Buschke and Löwenstein first described the giant condyloma in 1925 (which subsequently was named Buschke-Löwenstein tumor), there have been scattered reports over the past 90 years describing presentation and different avenues of treatment for patients with this condition. It is well known that immunocompromised individuals are at an increased risk of anogenital disease caused by human papillomavirus (HPV). In this report, we present the management of two HIV positive patients with giant condylomas. Both patients presented with urinary outflow obstruction and sepsis. Though giant condylomas are a rare phenomenon, these two cases underscore the importance of early treatment intervention, especially in the immunocompromised patient.
自1925年布施克和洛伊温斯坦首次描述巨大尖锐湿疣（随后被命名为布施克-洛伊温斯坦瘤）以来，在过去90年里有零星报道描述了这种疾病患者的临床表现和不同治疗途径。众所周知，免疫功能低下的个体感染人乳头瘤病毒（HPV）导致肛门生殖器疾病的风险增加。在本报告中，我们介绍了两名HIV阳性的巨大尖锐湿疣患者的治疗情况。两名患者均出现尿路梗阻和败血症。尽管巨大尖锐湿疣是一种罕见现象，但这两个病例强调了早期治疗干预的重要性，尤其是在免疫功能低下的患者中。
