Agarwal Sunil, Nirwal Gaurav Kumar, Singh Harendra
NIMS Medical College, Department of General Surgery, Jaipur, Rajasthan 303121, India.
NIMS Medical College, Department of General Surgery, Jaipur, Rajasthan 303121, India.
Int J Surg Case Rep. 2014;5(5):215-8. doi: 10.1016/j.ijscr.2014.01.023. Epub 2014 Feb 24.
Buschke-Löwenstein tumour, also known as Giant condyloma acuminatum, is a rare, sexually transmitted disease that affects ano-genital region. BLT is a slow growing cauliflower-like tumour, locally aggressive and destructive. Human papillomavirus has been identified as an important contributory factor in the development of tumour.
A 45 year uncircumcised male presented with complaints of cauliflower like growth on glans penis. Growth started as a small papule on the corona sulcus at 12 O'clock position 6 months back. Patient developed pain and dysuria due to compression of urethral meatus. Patient has history of multiple sexual partners.
BLT, first described by Buschke and Lowenstein in 1925. They observed a penile lesion that clinically resembled both common condyloma acuminata and squamous cell carcinoma, but differing from both of them regarding the biological behaviour and the histopathological appearance. GCA can be differentiated from ordinary condylomas by the characteristic "pushing" rather than "infiltrating" effect that tends to compress and displace the underlying tissue.
We have successfully treated a penile BLT with surgical excision and no relapse up to 6 months. Surgical excision could be considered an effective therapy in the treatment.
Buschke-Löwenstein肿瘤，也称为巨大尖锐湿疣，是一种罕见的性传播疾病，累及肛门生殖器区域。Buschke-Löwenstein肿瘤是一种生长缓慢的菜花状肿瘤，具有局部侵袭性和破坏性。人乳头瘤病毒已被确定为该肿瘤发生的一个重要促成因素。
一名45岁未行包皮环切术的男性因阴茎头出现菜花状肿物前来就诊。肿物6个月前开始于冠状沟12点位置出现一个小丘疹。由于尿道口受压，患者出现疼痛和排尿困难。患者有多个性伴侣史。
Buschke-Löwenstein肿瘤由Buschke和Lowenstein于1925年首次描述。他们观察到一个阴茎病变，在临床上既类似普通尖锐湿疣又类似鳞状细胞癌，但在生物学行为和组织病理学表现上与两者均不同。巨大尖锐湿疣可通过特征性的“推移”而非“浸润”效应与普通尖锐湿疣相鉴别，这种效应倾向于压迫和推移下方组织。
我们通过手术切除成功治疗了一例阴茎Buschke-Löwenstein肿瘤，随访6个月无复发。手术切除可被认为是一种有效的治疗方法。
