Kinser Patricia A, Lyon Debra E
Department of Family and Community Health Nursing, School of Nursing, Virginia Commonwealth University PO Box 980567, Richmond, Virginia, 23298-0567.
School of Nursing, University of Florida PO Box 100197, Gainesville, Florida, 32610-0197.
Brain Behav. 2014 Sep;4(5):665-74. doi: 10.1002/brb3.249. Epub 2014 Jul 10.
Depression is a chronic mental health condition that affects millions of individuals worldwide. It is well-established that psychological stress plays an integral role in depression and that depression has numerous negative health outcomes. However, a closer look at components of stress vulnerabilities and depression is required to allow for the development and testing of appropriate interventions.
This article describes a conceptual framework about the complex and bidirectional relationship between stress vulnerability, depression, and health outcomes in women. The authors elucidate how the framework can be applied in clinical research about cellular aging and on the mechanisms of complementary and alternative medicine (CAM) for depression, using yoga as an example of a CAM modality.
The proposed conceptual framework may be helpful for adding depth to the body of knowledge about the use of mind-body therapies for individuals at high risk of stress vulnerability and/or depression.
抑郁症是一种慢性心理健康状况，影响着全球数百万人。心理压力在抑郁症中起着不可或缺的作用，且抑郁症会产生众多负面健康后果，这一点已得到充分证实。然而，需要更深入地研究压力易感性和抑郁症的组成部分，以便开发和测试适当的干预措施。
本文描述了一个关于女性压力易感性、抑郁症和健康结果之间复杂双向关系的概念框架。作者以瑜伽这种补充和替代医学（CAM）模式为例，阐明了该框架如何应用于关于细胞衰老的临床研究以及抑郁症的补充和替代医学机制研究。
所提出的概念框架可能有助于深化关于身心疗法对处于压力易感性和/或抑郁症高风险个体的应用的知识体系。
