Yang J, Liu W Y, Song C Y
Zhong Xi Yi Jie He Za Zhi. 1989 Nov;9(11):677-8, 646.
The present study attempts to search the mechanism with which Zusanli regulates the gastrointestinal function by using radioimmunoassay to measure the contents of immunoreactive beta-endorphin (ir-beta-Ep) in gastrointestine, anterior lobe of the pituitary and plasma of the rats after electro-acupuncture of Zusanli. The findings showed that the contents of ir-beta-Ep in the gastroparietal mucous membrane, pyloric mucous membrane, duodenum, jejunum and ileum were significantly elevated 30 min after electro-acupuncture of Zusanli. But the contents of ir-beta-Ep in the anterior lobe of the pituitary and plasma were not changed. These results suggested that it may be through the endogenous opiate peptides in gastrointestine that Zusanli regulates the function of the gastrointestinal tract.
本研究试图通过放射免疫分析法测定大鼠足三里电针后胃肠道、垂体前叶及血浆中免疫反应性β-内啡肽(ir-β-Ep)的含量,以探寻足三里调节胃肠功能的机制。结果显示,足三里电针30分钟后,胃壁黏膜、幽门黏膜、十二指肠、空肠和回肠中ir-β-Ep的含量显著升高。但垂体前叶和血浆中ir-β-Ep的含量未发生变化。这些结果提示,足三里可能是通过胃肠道内的内源性阿片肽来调节胃肠道功能的。