Wirtz Carolin M, Radkovsky Anna, Ebert David D, Berking Matthias
Department of Clinical Psychology and Psychotherapy, University of Marburg, Marburg, Hesse, Germany; Department of Clinical Psychology and Psychotherapy, University of Erlangen- Nuremberg, Erlangen, Baveria, Germany.
Department of Clinical Psychology and Psychotherapy, University of Marburg, Marburg, Hesse, Germany.
PLoS One. 2014 Oct 20;9(10):e108288. doi: 10.1371/journal.pone.0108288. eCollection 2014.
Deficits in general emotion regulation (ER) skills have been linked to symptoms of depression and are thus considered a promising target in the treatment of Major depressive disorder (MDD). However, at this point, the extent to which such skills are relevant for coping with depression and whether they should instead be considered a transdiagnostic factor remain unclear. Therefore, the present study aimed to investigate whether successful ER skills application is associated with changes in depressive symptom severity (DSS), anxiety symptom severity (ASS), and general distress severity (GDS) over the course of treatment for MDD.
Successful ER skills application, DSS, ASS, and GDS were assessed four times during the first three weeks of treatment in 175 inpatients who met the criteria for MDD. We computed Pearson correlations to test whether successful ER skills application and the three indicators of psychopathology are cross-sectionally associated. We then performed latent growth curve modelling to test whether changes in successful ER skills application are negatively associated with a reduction of DSS, ASS, or GDS. Finally, we utilized latent change score models to examine whether successful ER skills application predicts subsequent reduction of DSS, ASS, or GDS.
Successful ER skills application was cross-sectionally associated with lower levels of DSS, ASS, and GDS at all points of assessment. An increase in successful skills application during treatment was associated with a decrease in DSS and GDS but not ASS. Finally, successful ER skills application predicted changes in subsequent DSS but neither changes in ASS nor changes in GDS.
Although general ER skills might be relevant for a broad range of psychopathological symptoms, they might be particularly important for the maintenance and treatment of depressive symptoms.
一般情绪调节（ER）技能缺陷与抑郁症状相关，因此被视为治疗重度抑郁症（MDD）的一个有前景的靶点。然而，目前尚不清楚这些技能在应对抑郁症方面的相关程度，以及它们是否应被视为一个跨诊断因素。因此，本研究旨在调查成功应用ER技能是否与MDD治疗过程中抑郁症状严重程度（DSS）、焦虑症状严重程度（ASS）和一般痛苦严重程度（GDS）的变化相关。
对175名符合MDD标准的住院患者在治疗的前三周内进行了四次成功应用ER技能、DSS、ASS和GDS的评估。我们计算了Pearson相关性，以测试成功应用ER技能与三种精神病理学指标是否存在横断面关联。然后，我们进行了潜在增长曲线建模，以测试成功应用ER技能的变化是否与DSS、ASS或GDS的降低呈负相关。最后，我们使用潜在变化分数模型来检验成功应用ER技能是否能预测DSS、ASS或GDS的后续降低。
在所有评估点上，成功应用ER技能与较低水平的DSS、ASS和GDS存在横断面关联。治疗期间成功应用技能的增加与DSS和GDS的降低相关，但与ASS无关。最后，成功应用ER技能可预测后续DSS的变化，但不能预测ASS或GDS的变化。
虽然一般的ER技能可能与广泛的精神病理症状相关，但它们可能对抑郁症状的维持和治疗尤为重要。
