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胎儿胆囊囊性畸形诊断中的超声评估与筛查征象

Evaluation and screening ultrasonic signs in the diagnosis of fetal biliary cystic malformation.

作者信息

Cong Xiang, Sun Xiubin, Liu Shaoping

机构信息

a Department of Ultrasound , Qilu Hospital of Shandong University , Jinan , P.R. China and.

b Department of Statistics , Public Health School of Shandong University , Jinan , P.R. China.

出版信息

J Matern Fetal Neonatal Med. 2015;28(17):2100-5. doi: 10.3109/14767058.2014.979148. Epub 2014 Nov 14.

Abstract

OBJECTIVE

To evaluate and screen for fetal biliary cystic malformation (BCM) associated-ultrasonic key signs or sign-combinations.

METHODS

Thirty cases of fetal abdominal cysts were investigated, followed up and divided into BCM and non-BCM groups. Expression rates of seven fetal BCM-associated ultrasonic signs in the two groups (A: the cyst was located in the right upper quadrant of the abdomen, B: located beneath the porta hepatis, C: having no septum, D: not the gallbladder, E: connected to the gallbladder, F: connected to the hepatic ducts, G: its inferior portion ended in the epigastric region, anterior to the spinal column) were compared. The diagnostic efficacy of single signs and sign-combinations was evaluated by diagnostic test.

RESULTS

The expressions of Sign A and Sign D had no statistically significant differences between the two groups. Single sign of B, F and G had diagnostic efficacy. The diagnostic index of B reached 1.8571. The diagnostic index of the sign-combinations B and D, F or G, and E or F or G reached 2.0000.

CONCLUSION

When the fetal cyst was located beneath the porta hepatis and was not the gallbladder, BCM could be diagnosed. Sign G might be another significant ultrasonic sign in BCM prenatal diagnosis.

摘要

目的

评估并筛选胎儿胆囊囊性畸形(BCM)相关的超声关键征象或征象组合。

方法

对30例胎儿腹部囊肿病例进行调查、随访,并分为BCM组和非BCM组。比较两组中七个与胎儿BCM相关的超声征象(A:囊肿位于腹部右上象限,B:位于肝门下方,C:无分隔,D:非胆囊,E:与胆囊相连,F:与肝管相连,G:其下部在脊柱前方的上腹部区域终止)的表达率。通过诊断试验评估单一征象及征象组合的诊断效能。

结果

两组间征象A和征象D的表达无统计学差异。单一征象B、F和G具有诊断效能。征象B的诊断指数达到1.8571。征象组合B和D、F或G以及E或F或G的诊断指数达到2.0000。

结论

当胎儿囊肿位于肝门下方且非胆囊时,可诊断为BCM。征象G可能是BCM产前诊断中的另一个重要超声征象。

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