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人类免疫缺陷病毒相关神经囊尾蚴病

HIV-Associated Neurocysticercosis.

作者信息

Anand Kuljeet Singh, Wadhwa Ankur, Garg Jyoti, Mahajan Rakesh Kumar

机构信息

Department of Neurology and Microbiology, Dr. R. M. L. Hospital, New Delhi, India.

Department of Neurology and Microbiology, Dr. R. M. L. Hospital, New Delhi, India

出版信息

J Int Assoc Provid AIDS Care. 2015 Mar-Apr;14(2):120-2. doi: 10.1177/2325957414555232. Epub 2014 Oct 20.

Abstract

Few cases of HIV and neurocysticercosis co-infection have been reported till date. The symptomatic manifestation of cysticercosis may be further reduced by interactions between the 2 disease processes. In patients with HIV, the diagnosis of neurocysticercosis is challenging and management must be individualized depending on the stage and the coexistent opportunistic conditions. We present 2 such cases. First was a 35-year-old driver seropositive for HIV-1 presented with complex partial seizures and a CD4 count of 530 cells/mm(3). The second case was a 40-year-old businessman with a CD4 count of 350 cells/mm(3). Both of them had multiple parenchymal lesions, with 1 being a large cystic lesion. Relatively high CD4 count and a positive enzyme-linked immunosorbent assay increased the likelihood for diagnosis and treatment. Both of our patients received cysticidal therapy, and none of them deteriorated with treatment.

摘要

迄今为止,仅有少数关于HIV与神经囊尾蚴病合并感染的病例报道。两种疾病进程之间的相互作用可能会进一步减轻囊尾蚴病的症状表现。对于HIV患者,神经囊尾蚴病的诊断具有挑战性,必须根据疾病阶段和并存的机会性疾病情况进行个体化管理。我们在此呈现2例这样的病例。第一例是一名35岁的司机,HIV-1血清学检测呈阳性,出现复杂部分性发作,CD4细胞计数为530个/立方毫米。第二例是一名40岁的商人,CD4细胞计数为350个/立方毫米。他们两人都有多个实质病变,其中1个是大的囊性病变。相对较高的CD4细胞计数和酶联免疫吸附试验阳性增加了诊断和治疗的可能性。我们的两名患者均接受了杀囊治疗,且均未因治疗而病情恶化。

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