Department of Gastroenterology and Hepatology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
Translational Gastroenterology Unit, University of Oxford, Oxford, UK.
Am J Gastroenterol. 2015 Jan;110(1):180-7. doi: 10.1038/ajg.2014.326. Epub 2014 Oct 21.
The Paris classification is an international classification system for describing polyp morphology. Thus far, the validity and reproducibility of this classification have not been assessed. We aimed to determine the interobserver agreement for the Paris classification among seven Western expert endoscopists.
A total of 85 short endoscopic video clips depicting polyps were created and assessed by seven expert endoscopists according to the Paris classification. After a digital training module, the same 85 polyps were assessed again. We calculated the interobserver agreement with a Fleiss kappa and as the proportion of pairwise agreement.
The interobserver agreement of the Paris classification among seven experts was moderate with a Fleiss kappa of 0.42 and a mean pairwise agreement of 67%. The proportion of lesions assessed as "flat" by the experts ranged between 13 and 40% (P<0.001). After the digital training, the interobserver agreement did not change (kappa 0.38, pairwise agreement 60%).
Our study is the first to validate the Paris classification for polyp morphology. We demonstrated only a moderate interobserver agreement among international Western experts for this classification system. Our data suggest that, in its current version, the use of this classification system in daily practice is questionable and it is unsuitable for comparative endoscopic research. We therefore suggest introduction of a simplification of the classification system.
巴黎分类法是一种用于描述息肉形态的国际分类系统。迄今为止,尚未评估该分类法的有效性和可重复性。我们旨在确定 7 位西方专家内镜医师对巴黎分类法的观察者间一致性。
共创建了 85 个短内镜视频片段,由 7 位专家内镜医师根据巴黎分类法进行评估。在进行数字培训模块后,再次评估相同的 85 个息肉。我们使用 Fleiss kappa 和成对一致性的比例来计算观察者间一致性。
7 位专家对巴黎分类法的观察者间一致性为中等,Fleiss kappa 为 0.42,平均成对一致性为 67%。专家评估的“平坦”病变比例在 13%至 40%之间(P<0.001)。数字培训后,观察者间一致性没有变化(kappa 0.38,成对一致性 60%)。
我们的研究首次验证了用于息肉形态的巴黎分类法。我们仅证明了国际西方专家对该分类系统的观察者间一致性为中等。我们的数据表明,在当前版本中,该分类系统在日常实践中的使用值得怀疑,不适合进行比较性内镜研究。因此,我们建议简化分类系统。