促黄体生成素释放激素类似物诺雷德治疗对雌二醇、孕酮及表皮生长因子与子宫平滑肌瘤结合的影响。
Effect of treatment with LHRH analogue Zoladex on binding of oestradiol, progesterone and epidermal growth factor to uterine fibromyomata.
作者信息
Baird D T, Bramley T A, Hawkins T A, Lumsden M A, West C P
机构信息
Department of Obstetrics and Gynaecology, University of Edinburgh, Centre for Reproductive Biology, UK.
出版信息
Horm Res. 1989;32 Suppl 1:154-6. doi: 10.1159/000181333.
PMID:2533146
Abstract
Treatment of patients with fibromyomata by Zoladex produces suppression of ovarian function. Receptor changes also occur in fibroids of women treated with Zoladex. The concentration of oestradiol receptors is significantly higher, whilst that of epidermal growth factor and progesterone is significantly lower.
摘要
用诺雷德治疗子宫肌瘤患者会导致卵巢功能受到抑制。接受诺雷德治疗的女性的肌瘤中也会发生受体变化。雌二醇受体的浓度显著更高，而表皮生长因子和孕酮的浓度则显著更低。
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