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巴布亚新几内亚一家三级医院中急性发热性疾病患者及登革热NS1检测呈阳性患者的患病率。

Prevalence of patients with acute febrile illnesses and positive dengue NS1 tests in a tertiary hospital in Papua New Guinea.

作者信息

Asigau Viola, Lavu Evelyn K, McBride William J H, Biloh Eric, Naroi Francis, Koana Egi, Ferguson John K, Laman Moses

机构信息

Pathology Laboratory, Port Moresby General Hospital, Port Moresby, Papua New Guinea; School of Medicine and Health Sciences, University of Papua New Guinea, Port Moresby, Papua New Guinea; Central Public Health Laboratory, Port Moresby General Hospital, Port Moresby, Papua New Guinea; James Cook University, School of Medicine and Dentistry, Cairns Base Hospital, Cairns, Australia; John Hunter Hospital, New Castle, New South Wales, Australia; Papua New Guinea Institute of Medical Research, Madang, Papua New Guinea.

Pathology Laboratory, Port Moresby General Hospital, Port Moresby, Papua New Guinea; School of Medicine and Health Sciences, University of Papua New Guinea, Port Moresby, Papua New Guinea; Central Public Health Laboratory, Port Moresby General Hospital, Port Moresby, Papua New Guinea; James Cook University, School of Medicine and Dentistry, Cairns Base Hospital, Cairns, Australia; John Hunter Hospital, New Castle, New South Wales, Australia; Papua New Guinea Institute of Medical Research, Madang, Papua New Guinea

出版信息

Am J Trop Med Hyg. 2015 Jan;92(1):72-4. doi: 10.4269/ajtmh.14-0373. Epub 2014 Oct 20.

Abstract

Because the prevalence of dengue fever in urban settings in Papua New Guinea is unknown, we investigated the presence of dengue using the NS1 antigen test in an outpatient-based prospective observational study at Port Moresby General Hospital. Of 140 patients with acute febrile illnesses, dengue fever was diagnosed in 14.9% (20 of 134; 95% confidence interval [95% CI] = 9.6-22.4). Malaria (2 of 137; 1.5%; 95% CI = 0.3-5.7), chikungunya (3 of 140; 2.1%; 95% CI = 0.6-6.6), and bacterial bloodstream infections (0 of 80; 0%; 95% CI = 0-5.7) were uncommon. Dengue fever should no longer be considered rare in Papua New Guinea.

摘要

由于巴布亚新几内亚城市地区登革热的流行情况未知,我们在莫尔斯比港总医院开展了一项基于门诊的前瞻性观察研究,使用NS1抗原检测法调查登革热的存在情况。在140例急性发热性疾病患者中,确诊登革热的患者占14.9%(134例中的20例;95%置信区间[95%CI]=9.6-22.4)。疟疾(137例中的2例;1.5%;95%CI=0.3-5.7)、基孔肯雅热(140例中的3例;2.1%;95%CI=0.6-6.6)和细菌性血流感染(80例中的0例;0%;95%CI=0-5.7)并不常见。在巴布亚新几内亚,登革热不应再被视为罕见疾病。

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