1 Minimally Invasive Surgery Unit, Division of General Surgery, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand ; 2 Digestive Disease Center, Showa University Northern Yokohama Hospital, 35-1 Chigasakichuo, Tsuzuki-ku, Yokohama 224-8503, Japan.
Ann Transl Med. 2014 Mar;2(3):31. doi: 10.3978/j.issn.2305-5839.2014.02.04.
Peroral endoscopic myotomy (POEM) is one of the alternative treatment for achalasia. Due to concept of natural orifice transluminal endoscopic surgery (NOTES), it becomes popular and widely accepted. With the endoluminal technique, submucosal tunnel was created followed by endoscopic myotomy. POEM is not only indicated in classical achalasia but also other abnormal esophageal motility disorders. Moreover, failures of endoscopic treatment or surgical attempted cases are not contraindicated for POEM. The second attempted POEM is also safe and technically feasible. Even though the legend of success of POEM is fruitful, the possible complications are very frightened. Good training and delicate practice will reduce rate of complications. This review provides a summary of current state-of-the-art of POEM, including indication equipments, technique and complications. This perfect procedure may become the treatment of choice of achalasia and some esophageal motility disorders in the near future.
经口内镜下肌切开术(POEM)是治疗贲门失弛缓症的一种替代治疗方法。由于经自然腔道内镜手术(NOTES)的概念,它变得流行并被广泛接受。通过腔内技术,在黏膜下创建隧道,然后进行内镜肌切开术。POEM 不仅适用于经典贲门失弛缓症,也适用于其他异常食管动力障碍。此外,内镜治疗失败或手术尝试失败的病例也不是 POEM 的禁忌证。第二次尝试 POEM 也是安全且技术上可行的。尽管 POEM 的成功传奇硕果累累,但可能出现的并发症却令人恐惧。良好的培训和精细的操作将降低并发症的发生率。本文综述了 POEM 的最新技术,包括适应证、设备、技术和并发症。这一完美的手术程序可能在不久的将来成为贲门失弛缓症和一些食管动力障碍的首选治疗方法。