Gutiérrez Fuentes J A, Gutiérrez Yago J J, Díez Monedero E, Alvarez Berceruelo J, Zamorano Curiel P, Tejerina Abanades L
Med Clin (Barc). 1989 Nov 11;93(15):565-7.
To evaluate whether lipoprotein Lp(a) favors the development of coronary atherosclerosis and may be considered as a risk factor for acute myocardial infarction, we studied 185 patients with this conditions who where compared with a control group. Total cholesterol and cholesterol bound to the several lipoprotein fractions were simultaneously evaluated. Comparisons were carried out, the subjects being subdivided into age groups of 40-49, 50-59 and more than 60 years; they were also subdivided depending on the level of Lp(a) cholesterol (lower than 25 mg/dl, between 25 and 50 mg/dl and higher than 50 mg/dl). Lp(a) appeared as indicative of a vascular risk in the younger groups. The incidence of myocardial infarction was higher when Lp(a) level was greater than 50 mg/dl.
为了评估脂蛋白Lp(a)是否促进冠状动脉粥样硬化的发展，并是否可被视为急性心肌梗死的一个危险因素，我们研究了185例患有这种病症的患者，并将其与一个对照组进行比较。同时评估了总胆固醇以及与几种脂蛋白组分结合的胆固醇。进行了比较，受试者被细分为40 - 49岁、50 - 59岁和60岁以上的年龄组；他们还根据Lp(a)胆固醇水平（低于25mg/dl、25至50mg/dl之间以及高于50mg/dl）进行了细分。Lp(a)在较年轻的年龄组中似乎是血管风险的一个指标。当Lp(a)水平大于50mg/dl时，心肌梗死的发生率更高。
