Siler-Fisher Angela, Tucci Veronica, Kalra Sarathi, Galwankar Sagar C, Khose Swapnil D, Sanjeevani S, Goel Ashish, Peacock Frank W
Department of Emergency Medicine, Baylor College of Medicine, Houston, India.
Department of Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, India.
Int J Crit Illn Inj Sci. 2014 Jul;4(3):261-5. doi: 10.4103/2229-5151.141482.
There have been many technological advances improving the work up and treatment of patients in the emergency department (ED). Point of care testing (POCT) is becoming more common, especially in the time compressed clinically high-pressured environment of the emergency department. In present times, emphasis of POCT has spurred search of novel biomarkers which promise earlier and more specific detection of disease. This article reviews the role of ST2, Galectin-3 and Adrenomedullin in the acute care setting addressing the screening, diagnostic, and prognostic role of each marker for stratification of patients. Use of these markers has shown a strong correlation with early identification and efficient management in the ED.
在急诊科(ED),已经有许多技术进步改善了对患者的检查和治疗。即时检验(POCT)正变得越来越普遍,尤其是在急诊科时间紧迫、临床压力大的环境中。目前,即时检验的重点促使人们寻找新的生物标志物,这些生物标志物有望更早、更特异性地检测疾病。本文综述了ST2、半乳糖凝集素-3和肾上腺髓质素在急性护理环境中的作用,探讨了每种标志物在患者分层中的筛查、诊断和预后作用。这些标志物的使用已显示出与急诊科的早期识别和有效管理密切相关。