Dang Dung T, Bosmans Ralph P G, Moitzi Christian, Voets Ilja K, Brunsveld Luc
Department of Biomedical Engineering, Eindhoven University of Technology, Den Dolech 2, 5612 AZ, Eindhoven, The Netherlands.
Org Biomol Chem. 2014 Dec 14;12(46):9341-4. doi: 10.1039/c4ob01729c. Epub 2014 Oct 22.
Supramolecular assembly of a beta-barrel protein via cucurbit[8]uril results in compact z-shaped protein dimers. SAXS data reveal the formation of a well ordered protein dimer, notwithstanding being connected by a reversible and flexible peptide linker, and highlight the supramolecular induced interplay of the proteins, analogous to covalently linked proteins.
通过葫芦[8]脲形成的β-桶状蛋白超分子组装体产生紧密的Z形蛋白二聚体。小角X射线散射数据揭示了尽管由可逆且灵活的肽接头连接，但仍形成了有序的蛋白二聚体，并突出了超分子诱导的蛋白间相互作用，类似于共价连接的蛋白。
