Elfeddali Iman, van der Feltz-Cornelis Christina M, van Os Jim, Knappe Susanne, Vieta Eduard, Wittchen Hans-Ulrich, Obradors-Tarragó Carla, Haro Josep Maria
Department of Health Promotion, School for Public Health and Primary Care (CAPHRI), Maastricht University, MD 6200, Maastricht, the Netherlands.
Tranzo Department, Tilburg University, LE 5000, Tilburg, The Netherlands.
Int J Environ Res Public Health. 2014 Oct 21;11(10):10915-39. doi: 10.3390/ijerph111010915.
Within the ROAMER project, which aims to provide a Roadmap for Mental Health Research in Europe, a two-stage Delphi survey among 86 European experts was conducted in order to identify research priorities in clinical mental health research. Expert consensus existed with regard to the importance of three challenges in the field of clinical mental health research: (1) the development of new, safe and effective interventions for mental disorders; (2) understanding the mechanisms of disease in order to be able to develop such new interventions; and (3) defining outcomes (an improved set of outcomes, including alternative outcomes) to use for clinical mental health research evaluation. Proposed actions involved increasing the utilization of tailored approaches (personalized medicine), developing blended eHealth/mHealth decision aids/guidance tools that help the clinician to choose between various treatment modalities, developing specific treatments in order to better target comorbidity and (further) development of biological, psychological and psychopharmacological interventions. The experts indicated that addressing these priorities will result in increased efficacy and impact across Europe; with a high probability of success, given that Europe has important strengths, such as skilled academics and a long research history. Finally, the experts stressed the importance of creating funding and coordinated networking as essential action needed in order to target the variety of challenges in clinical mental health research.
在旨在为欧洲心理健康研究提供路线图的“漫游者”项目中，对86位欧洲专家开展了两阶段的德尔菲调查，以确定临床心理健康研究的优先事项。专家们就临床心理健康研究领域三项挑战的重要性达成了共识：（1）开发针对精神障碍的新型、安全且有效的干预措施；（2）了解疾病机制以便能够开发此类新干预措施；（3）确定用于临床心理健康研究评估的结果（一套经过改进的结果，包括替代结果）。提议的行动包括提高量身定制方法（个性化医疗）的利用率，开发融合电子健康/移动健康的决策辅助工具/指导工具，以帮助临床医生在各种治疗方式之间进行选择，开发特定治疗方法以更好地针对合并症，以及（进一步）开发生物、心理和精神药理学干预措施。专家们表示，解决这些优先事项将提高整个欧洲的疗效和影响力；鉴于欧洲拥有诸如专业学者和悠久研究历史等重要优势，成功的可能性很大。最后，专家们强调了创建资金和协调网络的重要性，认为这是应对临床心理健康研究中各种挑战所需的基本行动。
