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一种导致梗阻性黄疸的胰腺浆液性囊腺瘤播散性变异型,一种非常罕见的实体:病例报告及文献复习

A disseminated variant of pancreatic serous cystadenoma causing obstructive jaundice, a very rare entity: a case report and review of the literature.

作者信息

Al-Jiffry Bilal O, Rayzah Fares, Khayat Samah H

机构信息

Department of Surgery, Taif University, PO Box 888, Taif 21947, Kingdom of Saudi Arabia.

出版信息

BMC Res Notes. 2014 Oct 22;7:749. doi: 10.1186/1756-0500-7-749.

Abstract

BACKGROUND

Microcystic adenoma or serous cystadenoma (SCA) is an uncommon tumor type, accounting for only 1-2% of pancreatic exocrine neoplasms. Usually unifocal, SCAs present as single, large, well-demarcated, multiloculated, cystic tumors, 1-25 cm in size.

CASE PRESENTATION

A 73-year-old man initially presented with epigastric abdominal pain and was diagnosed with SCA involving the whole pancreas. Eleven months later, he presented with obstructive jaundice, and total pancreatectomy was performed. The removed tissue allowed histological verification of pancreatic SCA. Histopathological examination showed both microcysts and macrocysts, lined by cuboidal epithelium, with optically clear cytoplasm and the absence of detectable mitosis or necrosis.

CONCLUSIONS

Thus, although relatively rare, pancreatic SCA is one of the differential diagnoses of epigastric abdominal pain; we recommend early surgical intervention for symptomatic pancreatic SCA.

摘要

背景

微囊性腺瘤或浆液性囊腺瘤(SCA)是一种罕见的肿瘤类型,仅占胰腺外分泌肿瘤的1%-2%。SCA通常为单发病灶,表现为单个、较大、边界清晰、多房性的囊性肿瘤,大小为1-25厘米。

病例介绍

一名73岁男性最初因上腹部疼痛就诊,被诊断为累及整个胰腺的SCA。11个月后,他出现梗阻性黄疸,接受了全胰切除术。切除的组织经组织学检查证实为胰腺SCA。组织病理学检查显示既有微囊肿又有大囊肿,内衬立方上皮,细胞质透明,未检测到有丝分裂或坏死。

结论

因此,尽管胰腺SCA相对罕见,但它是上腹部疼痛的鉴别诊断之一;我们建议对有症状的胰腺SCA进行早期手术干预。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a07/4213478/685049dd0c69/13104_2013_3263_Fig1_HTML.jpg

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