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血管成形术的机制——实验模型中的内镜和形态学研究

The mechanism of angioplasty--endoscopic and morphometric investigations in an experimental model.

作者信息

Ebner H, Wex P, Dragojevic D

机构信息

Gefäss-und Thoraxchirurgie, Marienkrankenhaus, Soest, Germany.

出版信息

Eur J Vasc Surg. 1989 Dec;3(6):543-7. doi: 10.1016/s0950-821x(89)80130-6.

DOI:10.1016/s0950-821x(89)80130-6
PMID:2533907
Abstract

The effect of angioplasty using two different sizes of balloon catheter were examined by angiography and angioscopy before and after dilatation. A significant increase in the outer and inner diameters was seen accompanied by a decrease in the cross sectional area of the stenoses as well as the thickness of the vascular wall. Angioscopy revealed typical longitudinal tears of the plaque edges which are pressed during flow against the vessel wall. Turbidity of saline could be seen after dilatation indicating possible rupture of the atheromatous plaque. These findings are discussed in the light of the mechanisms of angioplasty and the possible reasons for the good early and long-term results.

摘要

通过血管造影术和血管镜检查,在扩张前后对使用两种不同尺寸球囊导管进行血管成形术的效果进行了研究。观察到狭窄部位的外径和内径显著增加,同时狭窄部位的横截面积以及血管壁厚度减小。血管镜检查显示,斑块边缘出现典型的纵向撕裂,这些撕裂在血流过程中被压向血管壁。扩张后可见盐水变浑浊,提示动脉粥样硬化斑块可能破裂。根据血管成形术的机制以及取得良好早期和长期效果的可能原因对这些发现进行了讨论。

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