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在接受环形腹部整形术的肥胖症患者中,使用低浓度凝血酶的纤维蛋白胶可减少血清肿的形成。

The use of a fibrin glue with a low concentration of thrombin decreases seroma formation in postbariatric patients undergoing circular abdominoplasty.

作者信息

Pilone Vincenzo, Vitiello Antonio, Borriello Ciro, Gargiulo Stefano, Forestieri Pietro

机构信息

Department of Medicine and Surgery, University of Salerno, Via Giovanni Paolo II, 132, 84084, Fisciano Salerno, Italy.

出版信息

Obes Surg. 2015 Feb;25(2):354-9. doi: 10.1007/s11695-014-1467-8.

Abstract

BACKGROUND

The serum collection under the abdominal flap is the most common complication after a lipo-abdominoplasty. The frequency of seroma increases further among obese patients, who have achieved massive weight loss after bariatric surgery. The purpose of this study is to demonstrate the effectiveness of fibrin glues with a low concentration of thrombin in reducing seroma formation after a lipo-abdominoplasty.

METHODS

Thirty patients, that had achieved a significant weight loss after an intervention of laparoscopic adjustable gastric banding (LAGB), underwent a circular lipo-abdominoplasty at our bariatric surgery department. Patients were divided into two groups of 15 subjects each: group A underwent traditional surgery; in group B, we applied a slow-clotting variant of fibrin glue (ARTISS, Baxter) under the abdominal flap. All subjects were evaluated clinically using an ultrasound device on postoperative day 15. We considered positive for seroma, those cases with a liquid collection greater than 20 cc.

RESULTS

The groups were homogeneous for age, BMI, male/female ratio, and diabetic or smoker patients. The mean hospital stay was significantly longer in group A than in group B. We found eight cases of serum collection >20 cc in group A and only one case in group B. Hematoma, umbilicus necrosis, and surgical site infection occurred in both groups, but overall complication rate was lower in group B.

CONCLUSIONS

The use of a fibrin glue with a low concentration of thrombin could be useful during wound closure and may decrease seroma formation in postbariatric patients undergoing lipo-abdominoplasty.

摘要

背景

腹部皮瓣下血清积聚是抽脂腹部整形术后最常见的并发症。在减肥手术后体重大幅减轻的肥胖患者中,血清肿的发生率进一步增加。本研究的目的是证明低浓度凝血酶纤维蛋白胶在减少抽脂腹部整形术后血清肿形成方面的有效性。

方法

30例在腹腔镜可调节胃束带术(LAGB)干预后体重显著减轻的患者,在我们的减肥外科接受了环形抽脂腹部整形术。患者分为两组,每组15名受试者:A组接受传统手术;在B组中,我们在腹部皮瓣下应用了一种慢凝变体纤维蛋白胶(ARTISS,百特)。所有受试者在术后第15天使用超声设备进行临床评估。我们将液体收集量大于20 cc的病例视为血清肿阳性。

结果

两组在年龄、BMI、男女比例以及糖尿病或吸烟患者方面具有同质性。A组的平均住院时间明显长于B组。我们在A组中发现8例血清收集量>20 cc的病例,而在B组中只有1例。两组均发生了血肿、脐坏死和手术部位感染,但B组的总体并发症发生率较低。

结论

使用低浓度凝血酶的纤维蛋白胶在伤口闭合过程中可能有用,并可能减少接受抽脂腹部整形术的减肥后患者的血清肿形成。

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