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10
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本文引用的文献

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SPANDx: a genomics pipeline for comparative analysis of large haploid whole genome re-sequencing datasets.SPANDx：一种用于大型单倍体全基因组重测序数据集比较分析的基因组学流程。
BMC Res Notes. 2014 Sep 8;7:618. doi: 10.1186/1756-0500-7-618.
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Microevolution of Burkholderia pseudomallei during an acute infection.伯克霍尔德菌在急性感染期间的微观进化。
J Clin Microbiol. 2014 Sep;52(9):3418-21. doi: 10.1128/JCM.01219-14. Epub 2014 Jun 25.
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Complete Genome Sequence of the Encephalomyelitic Burkholderia pseudomallei Strain MSHR305.脑脊髓炎型类鼻疽伯克霍尔德菌菌株MSHR305的全基因组序列
Genome Announc. 2013 Aug 22;1(4):e00656-13. doi: 10.1128/genomeA.00656-13.
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Within-host evolution of Burkholderia pseudomallei over a twelve-year chronic carriage infection.十二年内携带伯氏考克斯体的个体中伯氏考克斯体的宿主内进化。
mBio. 2013 Jul 16;4(4):e00388-13. doi: 10.1128/mBio.00388-13.
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Melioidosis.类鼻疽
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Evolution of Burkholderia pseudomallei in recurrent melioidosis.伯克霍尔德氏菌在复发性类鼻疽中的进化。
PLoS One. 2012;7(5):e36507. doi: 10.1371/journal.pone.0036507. Epub 2012 May 15.
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Melioidosis at Royal Darwin Hospital in the big 2009-2010 wet season: comparison with the preceding 20 years.2009-2010 年大湿季期间皇家达尔文医院的类鼻疽病：与前 20 年的比较。
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A framework for variation discovery and genotyping using next-generation DNA sequencing data.利用下一代 DNA 测序数据进行变异发现和基因分型的框架。
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Integrative genomics viewer.整合基因组浏览器。
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progressiveMauve: multiple genome alignment with gene gain, loss and rearrangement.渐进紫：具有基因增益、缺失和重排的多基因组比对。
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从一例罕见类鼻疽病例中分离出的伯克霍尔德菌全基因组测序确定了具有相同多位点序列类型的多克隆感染。

Whole-genome sequencing of Burkholderia pseudomallei isolates from an unusual melioidosis case identifies a polyclonal infection with the same multilocus sequence type.

作者信息

Price Erin P, Sarovich Derek S, Viberg Linda, Mayo Mark, Kaestli Mirjam, Tuanyok Apichai, Foster Jeffrey T, Keim Paul, Pearson Talima, Currie Bart J

机构信息

Global and Tropical Health Division, Menzies School of Health Research, Darwin, Northern Territory, Australia Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, Arizona, USA

Global and Tropical Health Division, Menzies School of Health Research, Darwin, Northern Territory, Australia Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, Arizona, USA.

出版信息

J Clin Microbiol. 2015 Jan;53(1):282-6. doi: 10.1128/JCM.02560-14. Epub 2014 Oct 22.

DOI:10.1128/JCM.02560-14
PMID:25339397
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4290970/
Abstract

Twelve Burkholderia pseudomallei isolates collected over a 32-month period from a patient with chronic melioidosis demonstrated identical multilocus sequence types (STs). However, whole-genome sequencing suggests a polyclonal infection. This study is the first to report a mixed infection with the same ST.

摘要

在32个月的时间里，从一名慢性类鼻疽患者身上采集的12株伯克霍尔德菌假鼻疽分离株显示出相同的多位点序列类型（STs）。然而，全基因组测序表明这是一种多克隆感染。本研究首次报告了同一ST的混合感染。