从一例罕见类鼻疽病例中分离出的伯克霍尔德菌全基因组测序确定了具有相同多位点序列类型的多克隆感染。
Whole-genome sequencing of Burkholderia pseudomallei isolates from an unusual melioidosis case identifies a polyclonal infection with the same multilocus sequence type.
作者信息
Price Erin P, Sarovich Derek S, Viberg Linda, Mayo Mark, Kaestli Mirjam, Tuanyok Apichai, Foster Jeffrey T, Keim Paul, Pearson Talima, Currie Bart J
机构信息
Global and Tropical Health Division, Menzies School of Health Research, Darwin, Northern Territory, Australia Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, Arizona, USA
Global and Tropical Health Division, Menzies School of Health Research, Darwin, Northern Territory, Australia Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, Arizona, USA.
出版信息
J Clin Microbiol. 2015 Jan;53(1):282-6. doi: 10.1128/JCM.02560-14. Epub 2014 Oct 22.
Abstract
Twelve Burkholderia pseudomallei isolates collected over a 32-month period from a patient with chronic melioidosis demonstrated identical multilocus sequence types (STs). However, whole-genome sequencing suggests a polyclonal infection. This study is the first to report a mixed infection with the same ST.
摘要
在32个月的时间里，从一名慢性类鼻疽患者身上采集的12株伯克霍尔德菌假鼻疽分离株显示出相同的多位点序列类型（STs）。然而，全基因组测序表明这是一种多克隆感染。本研究首次报告了同一ST的混合感染。
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