Hoyer I, Gängler P, Will R, Benkert O
Zahn Mund Kieferheilkd Zentralbl. 1989;77(8):775-82.
The biocompatibility of the composite resin materials Exposit and Evicrol was tested by functional studies of the rat incisor and the biological test of the dental pulp of pigs. Exposit shows mainly reversible reactions of the vascular connective tissue both in the vital-microscopical examination of the immediate reaction and in short-term tests (24 hours, 7 days), where positive adaptation reactions (new vessels and revascularization) are to be observed. Evicrol causes distinct and irreversible damages in the pulp of the rat incisor. The results of the vital-microscopical examination are proven by histological checks of the rat incisor. In the morphological picture Exposit shows in pig teeth mainly slight and partly moderate inflammatory pulpal reactions after a period of 30 and 90 days. For Evicrol, however, severe reactions with a massive accumulation of inflammatory cells is to be observed after a period of 30 days. Despite an acceptable and, compared to Evicrol, a better biocompatibility of Exposit there is a demand for an exact pulp protection.
通过对大鼠门牙的功能研究和猪牙髓的生物学测试，对复合树脂材料Exposit和Evicrol的生物相容性进行了测试。在即时反应的活体显微镜检查和短期测试（24小时、7天）中，Exposit主要显示血管结缔组织的可逆反应，在这些测试中可观察到阳性适应反应（新血管和血管再生）。Evicrol对大鼠门牙牙髓造成明显且不可逆的损伤。大鼠门牙的活体显微镜检查结果通过组织学检查得到证实。在形态学图像中，Exposit在猪牙中30天和90天后主要显示轻微且部分为中度的牙髓炎症反应。然而，对于Evicrol，在30天后可观察到伴有大量炎症细胞积聚的严重反应。尽管Exposit具有可接受的生物相容性，且与Evicrol相比更好，但仍需要精确的牙髓保护。
