Itatani Ryo, Namimoto Tomohiro, Takaoka Hiroko, Katahira Kazuhiro, Morishita Syoji, Kitani Kosuke, Hamada Yasuyuki, Kitaoka Mitsuhiko, Nakaura Takeshi, Yamashita Yasuyuki
From the *Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University; Departments of †Radiology, ‡Urology, and §Pathology, Kumamoto Chuo Hospital; and ∥Department of Diagnostic Radiology, Amakusa Medical Center, Kumamoto, Japan.
J Comput Assist Tomogr. 2015 Jan-Feb;39(1):37-43. doi: 10.1097/RCT.0000000000000172.
The objective of this study was to assess whether adding isovoxel 3-dimensional T2-weighted imaging (volume isotropic T2-weighted acquisition [VISTA]) to multiparametric magnetic resonance imaging (mp-MRI) improves the ability to diagnose the extracapsular extension (ECE) of prostate cancer.
Two radiologists independently evaluated ECE on images acquired with mp-MRI only (method A) and mp-MRI plus VISTA (method B) in 50 men who had undergone prostatectomy. We also compared the signal-to-noise ratio of the tumor on T2WI and VISTA scans.
Sensitivity, specificity, and accuracy were higher with method B. For both readers, specificity, accuracy, and the area under the receiver operating characteristic curve of method B were significantly higher than those of method A (reader 1: P = 0.028, 0.025, and 0.006; reader 2: P = 0.017, 0.0071, and 0.018). The signal-to-noise ratio was significantly higher on T2-weighted imaging than VISTA images (9.21 [SD, 2.46] vs 7.30 [SD, 1.87], P < 0.01).
The addition of VISTA to mp-MRI improves the diagnostic value for ECE significantly.
本研究的目的是评估在多参数磁共振成像（mp-MRI）中添加等体素三维T2加权成像（容积各向同性T2加权采集[VISTA]）是否能提高诊断前列腺癌包膜外侵犯（ECE）的能力。
两名放射科医生独立评估了50例接受前列腺切除术的男性患者仅通过mp-MRI获取的图像（方法A）以及mp-MRI加VISTA获取的图像（方法B）上的ECE情况。我们还比较了T2WI和VISTA扫描上肿瘤的信噪比。
方法B的敏感性、特异性和准确性更高。对于两位阅片者，方法B的特异性、准确性和受试者操作特征曲线下面积均显著高于方法A（阅片者1：P = 0.028、0.025和0.006；阅片者2：P = 0.017、0.0071和0.018）。T2加权成像上的信噪比显著高于VISTA图像（9.21[标准差，2.46]对7.30[标准差，1.87]，P < 0.01）。
在mp-MRI中添加VISTA可显著提高ECE的诊断价值。
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