van Droogenbroeck J, Vermeulen A
Department of Endocrinology, University Hospital, Gent, Belgium.
Clin Endocrinol (Oxf). 1989 Oct;31(4):425-9. doi: 10.1111/j.1365-2265.1989.tb01266.x.
In distinction to Braunstein and Horton (1985) who reported an increase in maternal 5 alpha-androstane-3 alpha, 17 beta-diol glucuronide (ADG) plasma levels during pregnancy, we observed a decrease of these levels from the 10th week of pregnancy; the decrease parallels the decrease in dehydroepiandrosterone sulphate (DHEA-S) concentration. As the latter is a major precursor of ADG, the decrease in ADG levels during pregnancy is not unexpected and in line with the concept that ADG is a parameter of androgenicity.
与布劳恩施泰因和霍顿（1985年）的报告不同，他们发现孕期母体血浆中5α-雄烷-3α，17β-二醇葡糖苷酸（ADG）水平升高，而我们观察到从妊娠第10周起这些水平下降；这种下降与硫酸脱氢表雄酮（DHEA-S）浓度的下降平行。由于后者是ADG的主要前体，孕期ADG水平下降并不意外，且符合ADG是雄激素性参数的概念。
