Toyota Taro, Banno Taisuke, Nitta Sachiko, Takinoue Masahiro, Nomoto Tomonori, Natsume Yuno, Matsumura Shuichi, Fujinami Masanori
Department of Basic Science, Graduate School of Arts and Sciences, The University of Tokyo.
J Oleo Sci. 2014;63(11):1085-98. doi: 10.5650/jos.ess14190. Epub 2014 Oct 21.
This review briefly summarizes recent developments in the construction of biologically/environmentally compatible chemical machinery composed of soft matter. Since environmental and living systems are open systems, chemical machinery must continuously fulfill its functions not only through the influx and generation of molecules but also via the degradation and dissipation of molecules. If the degradation or dissipation of soft matter molecular building blocks and biomaterial molecules/polymers can be achieved, soft matter particles composed of them can be used to realize chemical machinery such as selfpropelled droplets, drug delivery carriers, tissue regeneration scaffolds, protocell models, cell-/tissuemarkers, and molecular computing systems.
本综述简要总结了由软物质构成的生物/环境兼容化学机器构建方面的最新进展。由于环境和生命系统是开放系统,化学机器不仅必须通过分子的流入和生成,而且还需经由分子的降解和耗散来持续履行其功能。如果能够实现软物质分子构建单元以及生物材料分子/聚合物的降解或耗散,那么由它们组成的软物质颗粒就可用于实现诸如自驱动液滴、药物递送载体、组织再生支架、原始细胞模型、细胞/组织标记物以及分子计算系统等化学机器。