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[Distributions and gene frequencies of PGM1 subtype, EsD, GLO1, AK, ADAand 6-PGD in 20 races of China].

作者信息

Li B L, Huang L, Zhou J, Qiu N

出版信息

Yi Chuan Xue Bao. 1989;16(2):151-8.

PMID:2534281
Abstract

The distributions and gene frequencies of PGM1, subtype EsD, GLO1, AK, ADA and 6-PGD of 4171 healthy donors in 20 races of China were detected using gel electrophoresis. Some isoenzymes such as PGM1, PGM1 subtype, EsD and GLO1 have better distribution and higher discriminating power than the others. Sixty-eight samples with PGM1(6) gene were observed in 12 races. The frequency in zhuang population is the highest among 20 races. The phenotype of PGM1 6-1 is up to 4.15%. The band of PGM1(6) of all 68 samples is in the same position in the gel. In general speaking, the gene frequencies of EsD in most races of southern part of China are higher than those of northern part. Phenotype EsD 2 in Hani, Lisu, Dai, Naxi, She, Zhuang, Dong, Miao are over 15%, Hani is up to 32.4%. The gene frequency of GLO1 in Tajik and Uygur are 0.297 and 0.2112 respectively. The others range from 0.0714 to 0.1527. In Qiang it is 0.0583. The gene frequencies of AK1. ADA1 and 6-PGDA are very high in 20 races, and with very low discriminating power.

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